Matches in SemOpenAlex for { <https://semopenalex.org/work/W2243369699> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2243369699 abstract "Primary aldosteronism (PA) is a common cause of resistant hypertension with a prevalence of approximately 20%. Spironolactone is the drug of choice for the medical management of patients with PA. Blacks have been reported to have low-renin HTN and respond better to diuretics and calcium channel blockers. Racial differences in response to spironolactone in patients with resistant hypertension have not been previously described. Consecutive subjects referred to the University of Alabama at Birmingham hypertension clinic for resistant hypertension had been evaluated with a plasma aldosterone concentration (PAC), plasma renin activity (PRA), and a 24-hr urine collection for aldosterone, sodium, and potassium during the patient’s usual diet. The BP response to spironolactone was compared retrospectively in patients. For clinical reasons, subjects had been treated with a median dose of 25 mg of spironolactone and the BP response at 6 weeks, 3 and 6 months was compared retrospectively. A total of 117 patients with resistant hypertension were included in the analysis, including 59 white and 58 black subjects. Both groups had a similar number of antihypertensive medications at baseline. PAC, PRA, U-aldo and serum potassium levels were also similar. BP reduction at 6-weeks, 3- and 6-months after treatment with spironolactone was similar in black and white subjects. At 3 months, the mean reduction in systolic BP was –19.5±19.0 and –23.2±20.0 for blacks and whites, respectively (p= 0.321). These data indicate that African American and white subjects with resistant hypertension respond equally well to spironolactone." @default.
- W2243369699 created "2016-06-24" @default.
- W2243369699 creator A5000505696 @default.
- W2243369699 creator A5002246155 @default.
- W2243369699 creator A5026714677 @default.
- W2243369699 creator A5043389439 @default.
- W2243369699 creator A5070837256 @default.
- W2243369699 creator A5071337091 @default.
- W2243369699 date "2008-01-01" @default.
- W2243369699 modified "2023-09-26" @default.
- W2243369699 title "Similar response to spironolactone in Whites and African-American patients with resistant hypertension" @default.
- W2243369699 hasPublicationYear "2008" @default.
- W2243369699 type Work @default.
- W2243369699 sameAs 2243369699 @default.
- W2243369699 citedByCount "0" @default.
- W2243369699 crossrefType "journal-article" @default.
- W2243369699 hasAuthorship W2243369699A5000505696 @default.
- W2243369699 hasAuthorship W2243369699A5002246155 @default.
- W2243369699 hasAuthorship W2243369699A5026714677 @default.
- W2243369699 hasAuthorship W2243369699A5043389439 @default.
- W2243369699 hasAuthorship W2243369699A5070837256 @default.
- W2243369699 hasAuthorship W2243369699A5071337091 @default.
- W2243369699 hasConcept C107130276 @default.
- W2243369699 hasConcept C126322002 @default.
- W2243369699 hasConcept C126894567 @default.
- W2243369699 hasConcept C134018914 @default.
- W2243369699 hasConcept C138976137 @default.
- W2243369699 hasConcept C164705383 @default.
- W2243369699 hasConcept C198710026 @default.
- W2243369699 hasConcept C2776379505 @default.
- W2243369699 hasConcept C2778525890 @default.
- W2243369699 hasConcept C2780233176 @default.
- W2243369699 hasConcept C2781222467 @default.
- W2243369699 hasConcept C3019558611 @default.
- W2243369699 hasConcept C71924100 @default.
- W2243369699 hasConcept C84393581 @default.
- W2243369699 hasConceptScore W2243369699C107130276 @default.
- W2243369699 hasConceptScore W2243369699C126322002 @default.
- W2243369699 hasConceptScore W2243369699C126894567 @default.
- W2243369699 hasConceptScore W2243369699C134018914 @default.
- W2243369699 hasConceptScore W2243369699C138976137 @default.
- W2243369699 hasConceptScore W2243369699C164705383 @default.
- W2243369699 hasConceptScore W2243369699C198710026 @default.
- W2243369699 hasConceptScore W2243369699C2776379505 @default.
- W2243369699 hasConceptScore W2243369699C2778525890 @default.
- W2243369699 hasConceptScore W2243369699C2780233176 @default.
- W2243369699 hasConceptScore W2243369699C2781222467 @default.
- W2243369699 hasConceptScore W2243369699C3019558611 @default.
- W2243369699 hasConceptScore W2243369699C71924100 @default.
- W2243369699 hasConceptScore W2243369699C84393581 @default.
- W2243369699 hasLocation W22433696991 @default.
- W2243369699 hasOpenAccess W2243369699 @default.
- W2243369699 hasPrimaryLocation W22433696991 @default.
- W2243369699 hasRelatedWork W1578008036 @default.
- W2243369699 hasRelatedWork W181389047 @default.
- W2243369699 hasRelatedWork W1968526070 @default.
- W2243369699 hasRelatedWork W2070620877 @default.
- W2243369699 hasRelatedWork W2130183902 @default.
- W2243369699 hasRelatedWork W2146361851 @default.
- W2243369699 hasRelatedWork W2151653301 @default.
- W2243369699 hasRelatedWork W2157965979 @default.
- W2243369699 hasRelatedWork W2161975266 @default.
- W2243369699 hasRelatedWork W2325377441 @default.
- W2243369699 hasRelatedWork W2395840757 @default.
- W2243369699 hasRelatedWork W2406394019 @default.
- W2243369699 hasRelatedWork W2418438129 @default.
- W2243369699 hasRelatedWork W2477869181 @default.
- W2243369699 hasRelatedWork W2586119386 @default.
- W2243369699 hasRelatedWork W2588743016 @default.
- W2243369699 hasRelatedWork W2735820175 @default.
- W2243369699 hasRelatedWork W2746916970 @default.
- W2243369699 hasRelatedWork W2800512696 @default.
- W2243369699 hasRelatedWork W3144675224 @default.
- W2243369699 hasVolume "118" @default.
- W2243369699 isParatext "false" @default.
- W2243369699 isRetracted "false" @default.
- W2243369699 magId "2243369699" @default.
- W2243369699 workType "article" @default.