Matches in SemOpenAlex for { <https://semopenalex.org/work/W2243388263> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2243388263 endingPage "4" @default.
- W2243388263 startingPage "371" @default.
- W2243388263 abstract "Acute liver failure either after liver resection or as part of underlying liver disease is still associated with high mortality. Hepatocyte transplantation in various forms has attracted attention recently. However, none of those reports have investigated the thorough and systematic analysis of effect of hepatocyte transplantation on acute liver failure induced by 90% hepatectomy. Therefore, we investigated systematic analysis of effect of hepatocyte transplantation on rats with acute liver failure.Male Sprague-Dawley rats were used. Group I rats (n = 26) received intrasplenic injection of 2 x 10(7) hepatocytes in 0.3 mL Dulbecco's modified Eagle's medium (DMEM) 24 hours prior to 90% hepatectomy. Group II rats (n = 24) received intrasplenic injection of DMEM only. Twenty-two rats from group I and 20 from group II were observed for the determination of survival time. The remaining 8 (4/each group) rats were used to assess the liver function and regeneration.The hepatocyte bearing spleen revealed active glucose-6-phosphatase activity. In group I rats, the survival was longer and that group had more long-term survivors than those of group II controls. In group I, there was significant increase in the ratio of weight of remnant liver lobes to body weight. At 24 hours after hepatectomy, group I rats had improved biochemical parameters compared to those of group II rats.In rats with acute liver failure, intrasplenic hepatocyte transplantation acts as a bridge to support experimental rats from acute liver failure to liver regeneration, prolong survival in rats with acute liver failure and improve biochemical parameters." @default.
- W2243388263 created "2016-06-24" @default.
- W2243388263 creator A5022881630 @default.
- W2243388263 creator A5030595367 @default.
- W2243388263 creator A5045933583 @default.
- W2243388263 creator A5061035322 @default.
- W2243388263 creator A5068466796 @default.
- W2243388263 creator A5076701540 @default.
- W2243388263 creator A5082165531 @default.
- W2243388263 date "2000-05-03" @default.
- W2243388263 modified "2023-09-23" @default.
- W2243388263 title "Systematic analysis of the effects of hepatocyte transplantation on rats with acute liver failure." @default.
- W2243388263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10791192" @default.
- W2243388263 hasPublicationYear "2000" @default.
- W2243388263 type Work @default.
- W2243388263 sameAs 2243388263 @default.
- W2243388263 citedByCount "4" @default.
- W2243388263 countsByYear W22433882632017 @default.
- W2243388263 countsByYear W22433882632018 @default.
- W2243388263 crossrefType "journal-article" @default.
- W2243388263 hasAuthorship W2243388263A5022881630 @default.
- W2243388263 hasAuthorship W2243388263A5030595367 @default.
- W2243388263 hasAuthorship W2243388263A5045933583 @default.
- W2243388263 hasAuthorship W2243388263A5061035322 @default.
- W2243388263 hasAuthorship W2243388263A5068466796 @default.
- W2243388263 hasAuthorship W2243388263A5076701540 @default.
- W2243388263 hasAuthorship W2243388263A5082165531 @default.
- W2243388263 hasConcept C126322002 @default.
- W2243388263 hasConcept C134018914 @default.
- W2243388263 hasConcept C141071460 @default.
- W2243388263 hasConcept C159110652 @default.
- W2243388263 hasConcept C171056886 @default.
- W2243388263 hasConcept C185592680 @default.
- W2243388263 hasConcept C202751555 @default.
- W2243388263 hasConcept C2776200302 @default.
- W2243388263 hasConcept C2776795407 @default.
- W2243388263 hasConcept C2776909242 @default.
- W2243388263 hasConcept C2779609443 @default.
- W2243388263 hasConcept C2911091166 @default.
- W2243388263 hasConcept C2992208098 @default.
- W2243388263 hasConcept C2994427840 @default.
- W2243388263 hasConcept C55493867 @default.
- W2243388263 hasConcept C71924100 @default.
- W2243388263 hasConcept C86803240 @default.
- W2243388263 hasConcept C90924648 @default.
- W2243388263 hasConcept C95444343 @default.
- W2243388263 hasConceptScore W2243388263C126322002 @default.
- W2243388263 hasConceptScore W2243388263C134018914 @default.
- W2243388263 hasConceptScore W2243388263C141071460 @default.
- W2243388263 hasConceptScore W2243388263C159110652 @default.
- W2243388263 hasConceptScore W2243388263C171056886 @default.
- W2243388263 hasConceptScore W2243388263C185592680 @default.
- W2243388263 hasConceptScore W2243388263C202751555 @default.
- W2243388263 hasConceptScore W2243388263C2776200302 @default.
- W2243388263 hasConceptScore W2243388263C2776795407 @default.
- W2243388263 hasConceptScore W2243388263C2776909242 @default.
- W2243388263 hasConceptScore W2243388263C2779609443 @default.
- W2243388263 hasConceptScore W2243388263C2911091166 @default.
- W2243388263 hasConceptScore W2243388263C2992208098 @default.
- W2243388263 hasConceptScore W2243388263C2994427840 @default.
- W2243388263 hasConceptScore W2243388263C55493867 @default.
- W2243388263 hasConceptScore W2243388263C71924100 @default.
- W2243388263 hasConceptScore W2243388263C86803240 @default.
- W2243388263 hasConceptScore W2243388263C90924648 @default.
- W2243388263 hasConceptScore W2243388263C95444343 @default.
- W2243388263 hasIssue "32" @default.
- W2243388263 hasLocation W22433882631 @default.
- W2243388263 hasOpenAccess W2243388263 @default.
- W2243388263 hasPrimaryLocation W22433882631 @default.
- W2243388263 hasRelatedWork W1992339915 @default.
- W2243388263 hasRelatedWork W2080417018 @default.
- W2243388263 hasRelatedWork W2243388263 @default.
- W2243388263 hasRelatedWork W2338231718 @default.
- W2243388263 hasRelatedWork W2413581047 @default.
- W2243388263 hasRelatedWork W2416477876 @default.
- W2243388263 hasRelatedWork W2477281997 @default.
- W2243388263 hasRelatedWork W2594925906 @default.
- W2243388263 hasRelatedWork W3022117979 @default.
- W2243388263 hasRelatedWork W3165619171 @default.
- W2243388263 hasVolume "47" @default.
- W2243388263 isParatext "false" @default.
- W2243388263 isRetracted "false" @default.
- W2243388263 magId "2243388263" @default.
- W2243388263 workType "article" @default.