Matches in SemOpenAlex for { <https://semopenalex.org/work/W2243988131> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2243988131 endingPage "606" @default.
- W2243988131 startingPage "600" @default.
- W2243988131 abstract "Purpose: Although traditional and current treatment strategies may demonstrate success, persistence or recurrence of difficult-to-heal wounds remain significant problems. A novel product, Hyalomatrix (Fidia Advanced Biopolymer, Abano Terme, Italy) is a bilayer of an benzyl esterified hyaluronan scaffold beneath a silicone membrane. The scaffold delivers hyaluronan to the wound, and the silicone membrane acts as a temporary epidermal barrier. We present the results obtained with Hyalomatrix in the treatment of difficult-to-heal wounds. Methods: From November, 2008 to March, 2010, Hyalomatrix has been used on total 10 patients with wounds that were expected difficult to heal with traditional and other current strategies. After average 37.4 days from development of wounds, Hyalomatrix was applied after wound debridement. On the average, Hyalomatrix application period was 17.6 days. After average 16.5 days from removal of Hyalomatrix, skin grafts was performed. Results: In all cases, regeneration of fibrous granulation tissues and edge re-epithelization were present after the application of the Hyalomatrix. And all of the previous inflammatory signs were reduced. After skin grafts, no adverse reactions were recorded in 9 cases. But in one case, postoperative wound infection occured due to a lack of efficient fibrous tissues. In this model, the Hyalomatrix acts as a hyaluronan delivery system and a barrier from the external environments. In tissue repair processes, the hyaluronan performs to facilitate the entry of a large number of cells into the wounds, to orientate the deposition of extracellular matrix fibrous components and to change the microenvironment of difficult-to-heal wounds. Conclusion: Our study suggests that Hyalomatrix could be a good and feasible approach for difficult-to-heal wounds. The Hyalomatrix improves microenvironments of difficult-to-heal wounds, reduces infection rates and physical stimulus despite of aggravating factors." @default.
- W2243988131 created "2016-06-24" @default.
- W2243988131 creator A5017237523 @default.
- W2243988131 creator A5019314304 @default.
- W2243988131 creator A5020273010 @default.
- W2243988131 creator A5020420921 @default.
- W2243988131 creator A5083728536 @default.
- W2243988131 date "2010-09-01" @default.
- W2243988131 modified "2023-09-23" @default.
- W2243988131 title "The Use of Hyalomatrix(R) in the Treatment of Difficult To Heal Wound" @default.
- W2243988131 cites W1888487585 @default.
- W2243988131 cites W1971711877 @default.
- W2243988131 cites W2015188671 @default.
- W2243988131 cites W2028145863 @default.
- W2243988131 cites W2060300324 @default.
- W2243988131 cites W2061095488 @default.
- W2243988131 cites W2091044550 @default.
- W2243988131 cites W2131281032 @default.
- W2243988131 cites W2144302911 @default.
- W2243988131 cites W2149672043 @default.
- W2243988131 hasPublicationYear "2010" @default.
- W2243988131 type Work @default.
- W2243988131 sameAs 2243988131 @default.
- W2243988131 citedByCount "0" @default.
- W2243988131 crossrefType "journal-article" @default.
- W2243988131 hasAuthorship W2243988131A5017237523 @default.
- W2243988131 hasAuthorship W2243988131A5019314304 @default.
- W2243988131 hasAuthorship W2243988131A5020273010 @default.
- W2243988131 hasAuthorship W2243988131A5020420921 @default.
- W2243988131 hasAuthorship W2243988131A5083728536 @default.
- W2243988131 hasConcept C105702510 @default.
- W2243988131 hasConcept C136229726 @default.
- W2243988131 hasConcept C141071460 @default.
- W2243988131 hasConcept C171056886 @default.
- W2243988131 hasConcept C185592680 @default.
- W2243988131 hasConcept C189165786 @default.
- W2243988131 hasConcept C2776055305 @default.
- W2243988131 hasConcept C2777438270 @default.
- W2243988131 hasConcept C2777529286 @default.
- W2243988131 hasConcept C2780269544 @default.
- W2243988131 hasConcept C55493867 @default.
- W2243988131 hasConcept C71924100 @default.
- W2243988131 hasConcept C86803240 @default.
- W2243988131 hasConcept C89429830 @default.
- W2243988131 hasConcept C95444343 @default.
- W2243988131 hasConceptScore W2243988131C105702510 @default.
- W2243988131 hasConceptScore W2243988131C136229726 @default.
- W2243988131 hasConceptScore W2243988131C141071460 @default.
- W2243988131 hasConceptScore W2243988131C171056886 @default.
- W2243988131 hasConceptScore W2243988131C185592680 @default.
- W2243988131 hasConceptScore W2243988131C189165786 @default.
- W2243988131 hasConceptScore W2243988131C2776055305 @default.
- W2243988131 hasConceptScore W2243988131C2777438270 @default.
- W2243988131 hasConceptScore W2243988131C2777529286 @default.
- W2243988131 hasConceptScore W2243988131C2780269544 @default.
- W2243988131 hasConceptScore W2243988131C55493867 @default.
- W2243988131 hasConceptScore W2243988131C71924100 @default.
- W2243988131 hasConceptScore W2243988131C86803240 @default.
- W2243988131 hasConceptScore W2243988131C89429830 @default.
- W2243988131 hasConceptScore W2243988131C95444343 @default.
- W2243988131 hasIssue "5" @default.
- W2243988131 hasLocation W22439881311 @default.
- W2243988131 hasOpenAccess W2243988131 @default.
- W2243988131 hasPrimaryLocation W22439881311 @default.
- W2243988131 hasRelatedWork W2064326093 @default.
- W2243988131 hasRelatedWork W2113864595 @default.
- W2243988131 hasRelatedWork W2214110491 @default.
- W2243988131 hasRelatedWork W2257051283 @default.
- W2243988131 hasRelatedWork W2305265900 @default.
- W2243988131 hasRelatedWork W2319489690 @default.
- W2243988131 hasRelatedWork W2328710980 @default.
- W2243988131 hasRelatedWork W2382404711 @default.
- W2243988131 hasRelatedWork W2500216592 @default.
- W2243988131 hasRelatedWork W2801733343 @default.
- W2243988131 hasRelatedWork W2803131469 @default.
- W2243988131 hasRelatedWork W2805073416 @default.
- W2243988131 hasRelatedWork W2903171613 @default.
- W2243988131 hasRelatedWork W2955524803 @default.
- W2243988131 hasRelatedWork W3037788085 @default.
- W2243988131 hasRelatedWork W3169906910 @default.
- W2243988131 hasRelatedWork W92163770 @default.
- W2243988131 hasRelatedWork W97185056 @default.
- W2243988131 hasRelatedWork W2188625014 @default.
- W2243988131 hasRelatedWork W45851954 @default.
- W2243988131 hasVolume "37" @default.
- W2243988131 isParatext "false" @default.
- W2243988131 isRetracted "false" @default.
- W2243988131 magId "2243988131" @default.
- W2243988131 workType "article" @default.