Matches in SemOpenAlex for { <https://semopenalex.org/work/W2244052227> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2244052227 endingPage "H1127" @default.
- W2244052227 startingPage "H1119" @default.
- W2244052227 abstract "The role of adenosine for reactive hyperemia in normal and stunned myocardium was examined in 16 open-chest barbiturate-anesthetized pigs. Interstitial adenosine concentration was reduced or enhanced by intracoronary infusion of adenosine deaminase or the nucleoside transport inhibitor R 75231, respectively. In normal myocardium, adenosine deaminase reduced volume of hyperemia (Doppler flowmetry) after a 30-s left anterior descending coronary artery (LAD) occlusion by 20% (6-34%; P < 0.05), whereas R 75231 increased volume of hyperemia by 15% (2-24%; P < 0.05). Adenosine deaminase reduced volume of hyperemia after a 2-min LAD occlusion by 27% (13-37%; P < 0.001), whereas R 75231 increased volume of hyperemia by 66% (53-159%; P < 0.001). Adenosine deaminase and R 75231 did not affect maximal hyperemia. Volume of hyperemia after a 2-min LAD occlusion was reduced in stunned myocardium (%systolic segment length shortening reduced by approximately 45%, ultrasonic technique) but not further altered by either adenosine deaminase or R 75231. These findings show that adenosine contributes to reactive hyperemia after 30-120 s of ischemia in normal myocardium and indicate that the reduced reactive hyperemia in stunned myocardium is due to reduced accumulation of adenosine during ischemia." @default.
- W2244052227 created "2016-06-24" @default.
- W2244052227 creator A5030862058 @default.
- W2244052227 creator A5054567242 @default.
- W2244052227 creator A5084406559 @default.
- W2244052227 creator A5086252276 @default.
- W2244052227 date "1992-10-01" @default.
- W2244052227 modified "2023-09-30" @default.
- W2244052227 title "Role of adenosine for reactive hyperemia in normal and stunned porcine myocardium" @default.
- W2244052227 doi "https://doi.org/10.1152/ajpheart.1992.263.4.h1119" @default.
- W2244052227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1415760" @default.
- W2244052227 hasPublicationYear "1992" @default.
- W2244052227 type Work @default.
- W2244052227 sameAs 2244052227 @default.
- W2244052227 citedByCount "14" @default.
- W2244052227 countsByYear W22440522272014 @default.
- W2244052227 countsByYear W22440522272016 @default.
- W2244052227 crossrefType "journal-article" @default.
- W2244052227 hasAuthorship W2244052227A5030862058 @default.
- W2244052227 hasAuthorship W2244052227A5054567242 @default.
- W2244052227 hasAuthorship W2244052227A5084406559 @default.
- W2244052227 hasAuthorship W2244052227A5086252276 @default.
- W2244052227 hasConcept C126322002 @default.
- W2244052227 hasConcept C158846371 @default.
- W2244052227 hasConcept C164705383 @default.
- W2244052227 hasConcept C185592680 @default.
- W2244052227 hasConcept C2776268601 @default.
- W2244052227 hasConcept C2776991684 @default.
- W2244052227 hasConcept C3019128504 @default.
- W2244052227 hasConcept C34628245 @default.
- W2244052227 hasConcept C42219234 @default.
- W2244052227 hasConcept C541997718 @default.
- W2244052227 hasConcept C71924100 @default.
- W2244052227 hasConceptScore W2244052227C126322002 @default.
- W2244052227 hasConceptScore W2244052227C158846371 @default.
- W2244052227 hasConceptScore W2244052227C164705383 @default.
- W2244052227 hasConceptScore W2244052227C185592680 @default.
- W2244052227 hasConceptScore W2244052227C2776268601 @default.
- W2244052227 hasConceptScore W2244052227C2776991684 @default.
- W2244052227 hasConceptScore W2244052227C3019128504 @default.
- W2244052227 hasConceptScore W2244052227C34628245 @default.
- W2244052227 hasConceptScore W2244052227C42219234 @default.
- W2244052227 hasConceptScore W2244052227C541997718 @default.
- W2244052227 hasConceptScore W2244052227C71924100 @default.
- W2244052227 hasIssue "4" @default.
- W2244052227 hasLocation W22440522271 @default.
- W2244052227 hasLocation W22440522272 @default.
- W2244052227 hasOpenAccess W2244052227 @default.
- W2244052227 hasPrimaryLocation W22440522271 @default.
- W2244052227 hasRelatedWork W1615266951 @default.
- W2244052227 hasRelatedWork W2017770252 @default.
- W2244052227 hasRelatedWork W2056270585 @default.
- W2244052227 hasRelatedWork W2106057349 @default.
- W2244052227 hasRelatedWork W2244052227 @default.
- W2244052227 hasRelatedWork W2320914227 @default.
- W2244052227 hasRelatedWork W2403710964 @default.
- W2244052227 hasRelatedWork W2411302374 @default.
- W2244052227 hasRelatedWork W3147081201 @default.
- W2244052227 hasRelatedWork W4290220017 @default.
- W2244052227 hasVolume "263" @default.
- W2244052227 isParatext "false" @default.
- W2244052227 isRetracted "false" @default.
- W2244052227 magId "2244052227" @default.
- W2244052227 workType "article" @default.