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- W2244455787 abstract "Summary. 1. High pressure oxygen increases the sensitivity of mice to x-rays. 2. Methemoglobin producing drugs, antioxidants and sulfhydryl compounds do not increase the survival of mice exposed to five atmospheres of oxygen. 3. High partial pressures of CO2 provide a measurable radioprotective egfect in mice. 4. N-hydroxy-p-aminopropiopenone appears to be the metabolite of PAPP responsible for the production of methemoglobinemia in experimental animals. 5. The metabolism of PAPP is complex; seven compounds have been identified and at least two remain to be identified in mouse urine. 6. Benzhydrazide will prevent the production of methemoglobin by PAPP both in vivo and in vitro, presumably by blocking the N-hydroxylating enzymatic pathway." @default.
- W2244455787 created "2016-06-24" @default.
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- W2244455787 date "1970-05-25" @default.
- W2244455787 modified "2023-09-27" @default.
- W2244455787 title "Hypoxia and para-aminopropiophenone as radioprotective agents. Final report" @default.
- W2244455787 doi "https://doi.org/10.2172/4110570" @default.
- W2244455787 hasPublicationYear "1970" @default.
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