Matches in SemOpenAlex for { <https://semopenalex.org/work/W2244731059> ?p ?o ?g. }
- W2244731059 endingPage "C412" @default.
- W2244731059 startingPage "C399" @default.
- W2244731059 abstract "Nonelectrogenic movement of Cl- is believed to be responsible for the active accumulation of intracellular Cl- in cardiac muscle. The electro-neutral pathways underlying this nonpassive distribution of Cl- are believed to include Cl(-)-HCO3- exchange, Na(+)-dependent cotransport (operating as Na(+)-Cl- and Na(+)-K(+)-2Cl- cotransport), and K(+)-Cl- cotransport. The electrogenic movement of Cl- in cardiac muscle is particularly interesting from a historical perspective. Until recently, there was some doubt as to whether Cl- carried any current in the heart. Early microelectrode experiments indicated that a Cl- conductance probably played an important role in regulating action potential duration and resting membrane potential. Subsequent voltage-clamp experiments identified a repolarizing, transient outward current that was believed to be conducted by Cl-, yet further investigation suggested that this transient outward current was more likely a K+ current, not a Cl- current. This left some doubt as to whether Cl- played any role in regulating membrane potential in cardiac muscle. More recent studies, however, have identified a highly selective Cl- conductance that is regulated by intracellular adenosine 3',5'-cyclic monophosphate, and it appears that this Cl- current may play an important role in the regulation of action potential duration and resting membrane potential." @default.
- W2244731059 created "2016-06-24" @default.
- W2244731059 creator A5066498895 @default.
- W2244731059 creator A5079623066 @default.
- W2244731059 date "1991-09-01" @default.
- W2244731059 modified "2023-10-16" @default.
- W2244731059 title "Chloride conductance pathways in heart" @default.
- W2244731059 cites W1553673732 @default.
- W2244731059 cites W1965532418 @default.
- W2244731059 cites W1967561799 @default.
- W2244731059 cites W1969849820 @default.
- W2244731059 cites W1975852834 @default.
- W2244731059 cites W1976496460 @default.
- W2244731059 cites W1976780891 @default.
- W2244731059 cites W1978059245 @default.
- W2244731059 cites W1979215394 @default.
- W2244731059 cites W1984241500 @default.
- W2244731059 cites W1985495968 @default.
- W2244731059 cites W1987051971 @default.
- W2244731059 cites W1988577370 @default.
- W2244731059 cites W1991075546 @default.
- W2244731059 cites W1991639569 @default.
- W2244731059 cites W1992532194 @default.
- W2244731059 cites W1999640868 @default.
- W2244731059 cites W2001114837 @default.
- W2244731059 cites W2002733374 @default.
- W2244731059 cites W2004582891 @default.
- W2244731059 cites W2005219247 @default.
- W2244731059 cites W2006252556 @default.
- W2244731059 cites W2009292667 @default.
- W2244731059 cites W2009667219 @default.
- W2244731059 cites W2011920501 @default.
- W2244731059 cites W2013011061 @default.
- W2244731059 cites W2017654428 @default.
- W2244731059 cites W2022730533 @default.
- W2244731059 cites W2024770714 @default.
- W2244731059 cites W2025733059 @default.
- W2244731059 cites W2028618800 @default.
- W2244731059 cites W2028842585 @default.
- W2244731059 cites W2028982633 @default.
- W2244731059 cites W2029891070 @default.
- W2244731059 cites W2030668240 @default.
- W2244731059 cites W2031920967 @default.
- W2244731059 cites W2032144299 @default.
- W2244731059 cites W2033045833 @default.
- W2244731059 cites W2034637528 @default.
- W2244731059 cites W2036383484 @default.
- W2244731059 cites W2038807786 @default.
- W2244731059 cites W2041469157 @default.
- W2244731059 cites W2042217106 @default.
- W2244731059 cites W2045063545 @default.
- W2244731059 cites W2045547109 @default.
- W2244731059 cites W2046968848 @default.
- W2244731059 cites W2049049507 @default.
- W2244731059 cites W2052619676 @default.
- W2244731059 cites W2058626030 @default.
- W2244731059 cites W2065988853 @default.
- W2244731059 cites W2067312729 @default.
- W2244731059 cites W2067783737 @default.
- W2244731059 cites W2071293796 @default.
- W2244731059 cites W2073474023 @default.
- W2244731059 cites W2074501443 @default.
- W2244731059 cites W2076353055 @default.
- W2244731059 cites W2078081709 @default.
- W2244731059 cites W2078556968 @default.
- W2244731059 cites W2081301825 @default.
- W2244731059 cites W2082066498 @default.
- W2244731059 cites W2083213678 @default.
- W2244731059 cites W2085134206 @default.
- W2244731059 cites W2088462035 @default.
- W2244731059 cites W2099802890 @default.
- W2244731059 cites W2100548210 @default.
- W2244731059 cites W2100955490 @default.
- W2244731059 cites W2105609457 @default.
- W2244731059 cites W2108335198 @default.
- W2244731059 cites W2109817588 @default.
- W2244731059 cites W2118581859 @default.
- W2244731059 cites W2120160505 @default.
- W2244731059 cites W2123184686 @default.
- W2244731059 cites W2125551003 @default.
- W2244731059 cites W2125976543 @default.
- W2244731059 cites W2134921936 @default.
- W2244731059 cites W2136297988 @default.
- W2244731059 cites W2137067311 @default.
- W2244731059 cites W2137926032 @default.
- W2244731059 cites W2141454385 @default.
- W2244731059 cites W2142748206 @default.
- W2244731059 cites W2143183230 @default.
- W2244731059 cites W2147142035 @default.
- W2244731059 cites W2156441977 @default.
- W2244731059 cites W2167744805 @default.
- W2244731059 cites W2175682714 @default.
- W2244731059 cites W2314333033 @default.
- W2244731059 doi "https://doi.org/10.1152/ajpcell.1991.261.3.c399" @default.
- W2244731059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1716049" @default.
- W2244731059 hasPublicationYear "1991" @default.
- W2244731059 type Work @default.
- W2244731059 sameAs 2244731059 @default.