Matches in SemOpenAlex for { <https://semopenalex.org/work/W2245882012> ?p ?o ?g. }
- W2245882012 abstract "Background: In preoperative assessment of breast cancer, MRI has been shown to identify more additional breast lesions than are detectable using conventional imaging techniques. The characterization of additional lesions is more important than detection for optimal surgical treatment. Additional breast lesions can be included in focus, mass, and non-mass enhancement (NME) on MRI. According to the fifth edition of the breast imaging reporting and data system (BI-RADS®), which includes several changes in the NME descriptors, few studies to date have evaluated NME in preoperative assessment of breast cancer. Objectives: We investigated the diagnostic accuracy of BI-RADS descriptors in predicting malignancy for additional NME lesions detected on preoperative 3T dynamic contrast enhanced MRI (DCE-MRI) in patients with newly diagnosed breast cancer. Patients and Methods: Between January 2008 and December 2012, 88 patients were enrolled in our study, all with NME lesions other than the index cancer on preoperative 3T DCE-MRI and all with accompanying histopathologic examination. The MRI findings were analyzed according to the BI-RADS MRI lexicon. We evaluated the size, distribution, internal enhancement pattern, and location of NME lesions relative to the index cancer (i.e., same quadrant, different quadrant, or contralateral breast). Results: On histopathologic analysis of the 88 NME lesions, 73 (83%) were malignant and 15 (17%) were benign. Lesion size did not differ significantly between malignant and benign lesions (P = 0.410). Malignancy was more frequent in linear (P = 0.005) and segmental (P = 0.011) distributions, and benignancy was more frequent in focal (P = 0.004) and regional (P < 0.001) NME lesions. The highest positive predictive value (PPV) for malignancy occurred in segmental (96.8%), linear (95.1%), clustered ring (100%), and clumped (92.0%) enhancement. Asymmetry demonstrated a high positive predictive value of 85.9%. The frequency of malignancy was higher for NME lesions located in the same quadrant with the index cancer (P = 0.006), and benignancy was higher in the contralateral breast (P = 0.015). On multivariate analysis, linear (P = 0.001) and segmental (P = 0.005) distributions were significant predictors of malignancy. Conclusion: The possibility of malignancy is strongly indicated when additional NME lesions show linear or segmental enhancement on preoperative 3T DCE-MRI in patients with recently diagnosed breast cancer." @default.
- W2245882012 created "2016-06-24" @default.
- W2245882012 creator A5004634376 @default.
- W2245882012 creator A5005247497 @default.
- W2245882012 creator A5050470993 @default.
- W2245882012 creator A5051554711 @default.
- W2245882012 creator A5077492621 @default.
- W2245882012 creator A5080610278 @default.
- W2245882012 creator A5089714011 @default.
- W2245882012 date "2016-01-23" @default.
- W2245882012 modified "2023-10-01" @default.
- W2245882012 title "Significance of Additional Non-Mass Enhancement in Patients with Breast Cancer on Preoperative 3T Dynamic Contrast Enhanced MRI of the Breast" @default.
- W2245882012 cites W1523062753 @default.
- W2245882012 cites W1974334892 @default.
- W2245882012 cites W2003188860 @default.
- W2245882012 cites W2032515605 @default.
- W2245882012 cites W2043097442 @default.
- W2245882012 cites W2045762827 @default.
- W2245882012 cites W2046930507 @default.
- W2245882012 cites W2056214995 @default.
- W2245882012 cites W2065955219 @default.
- W2245882012 cites W2082199330 @default.
- W2245882012 cites W2088244290 @default.
- W2245882012 cites W2093560645 @default.
- W2245882012 cites W2097974869 @default.
- W2245882012 cites W2109909368 @default.
- W2245882012 cites W2111978764 @default.
- W2245882012 cites W2113649907 @default.
- W2245882012 cites W2115565566 @default.
- W2245882012 cites W2122647939 @default.
- W2245882012 cites W2131739776 @default.
- W2245882012 cites W2137344154 @default.
- W2245882012 cites W2139641915 @default.
- W2245882012 cites W2158832504 @default.
- W2245882012 cites W2163856492 @default.
- W2245882012 cites W2184426873 @default.
- W2245882012 cites W86091869 @default.
- W2245882012 doi "https://doi.org/10.5812/iranjradiol.30909" @default.
- W2245882012 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4841862" @default.
- W2245882012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27127579" @default.
- W2245882012 hasPublicationYear "2016" @default.
- W2245882012 type Work @default.
- W2245882012 sameAs 2245882012 @default.
- W2245882012 citedByCount "9" @default.
- W2245882012 countsByYear W22458820122016 @default.
- W2245882012 countsByYear W22458820122017 @default.
- W2245882012 countsByYear W22458820122018 @default.
- W2245882012 countsByYear W22458820122019 @default.
- W2245882012 countsByYear W22458820122021 @default.
- W2245882012 countsByYear W22458820122022 @default.
- W2245882012 countsByYear W22458820122023 @default.
- W2245882012 crossrefType "journal-article" @default.
- W2245882012 hasAuthorship W2245882012A5004634376 @default.
- W2245882012 hasAuthorship W2245882012A5005247497 @default.
- W2245882012 hasAuthorship W2245882012A5050470993 @default.
- W2245882012 hasAuthorship W2245882012A5051554711 @default.
- W2245882012 hasAuthorship W2245882012A5077492621 @default.
- W2245882012 hasAuthorship W2245882012A5080610278 @default.
- W2245882012 hasAuthorship W2245882012A5089714011 @default.
- W2245882012 hasBestOaLocation W22458820121 @default.
- W2245882012 hasConcept C121608353 @default.
- W2245882012 hasConcept C126322002 @default.
- W2245882012 hasConcept C126838900 @default.
- W2245882012 hasConcept C142724271 @default.
- W2245882012 hasConcept C143409427 @default.
- W2245882012 hasConcept C2777111374 @default.
- W2245882012 hasConcept C2777432617 @default.
- W2245882012 hasConcept C2779399171 @default.
- W2245882012 hasConcept C2780472235 @default.
- W2245882012 hasConcept C2780639617 @default.
- W2245882012 hasConcept C2781156865 @default.
- W2245882012 hasConcept C2989005 @default.
- W2245882012 hasConcept C530470458 @default.
- W2245882012 hasConcept C71924100 @default.
- W2245882012 hasConceptScore W2245882012C121608353 @default.
- W2245882012 hasConceptScore W2245882012C126322002 @default.
- W2245882012 hasConceptScore W2245882012C126838900 @default.
- W2245882012 hasConceptScore W2245882012C142724271 @default.
- W2245882012 hasConceptScore W2245882012C143409427 @default.
- W2245882012 hasConceptScore W2245882012C2777111374 @default.
- W2245882012 hasConceptScore W2245882012C2777432617 @default.
- W2245882012 hasConceptScore W2245882012C2779399171 @default.
- W2245882012 hasConceptScore W2245882012C2780472235 @default.
- W2245882012 hasConceptScore W2245882012C2780639617 @default.
- W2245882012 hasConceptScore W2245882012C2781156865 @default.
- W2245882012 hasConceptScore W2245882012C2989005 @default.
- W2245882012 hasConceptScore W2245882012C530470458 @default.
- W2245882012 hasConceptScore W2245882012C71924100 @default.
- W2245882012 hasIssue "1" @default.
- W2245882012 hasLocation W22458820121 @default.
- W2245882012 hasLocation W22458820122 @default.
- W2245882012 hasLocation W22458820123 @default.
- W2245882012 hasLocation W22458820124 @default.
- W2245882012 hasOpenAccess W2245882012 @default.
- W2245882012 hasPrimaryLocation W22458820121 @default.
- W2245882012 hasRelatedWork W1517187278 @default.
- W2245882012 hasRelatedWork W2060460808 @default.
- W2245882012 hasRelatedWork W2093929361 @default.
- W2245882012 hasRelatedWork W2094838815 @default.
- W2245882012 hasRelatedWork W2111092438 @default.