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- W2246142125 abstract "Experiments were carried out with 185 to 200-g male white rats exposed to 1000 r of gamma radiation at 100 r/min. Early disturbances in nerve cells are expressed in a sharp shift of the isoelectric points of ribonucleoproteids (RNP) in the mitochondria and tigroid toward the alkali direction Quantitative variations of isoelectric points in the mitochondria and tigroid of various neurons were studied at one-minute intervals, starting with the first hour. The data indicate the strongest isoelectric shift characterizes the afferent ganglion cell mitochondria. One minute after exposure the isoelectric shift reached 0.9 to 1.0 on the pH scale in 5 min it increased 1.2 and in 10 min 1.4. After 12 Bin, the shift decreased, and after 17 min a drop was clearly observed (0.5). After 30 to 60 min the shift is only O.S to 0.6. Isoelectric point shifts in mitochondria and tigroid RNP in the spinal cord ganglia nerve cells, in spinal motor cells, and in the cells of the third and fourth layer of the sincipital cerebral cortex are plotted (in pH units) for various interwals following irradiation. The initial isoelectric point changes are interpreted as a form of protective mechanism against radiation injuries. (R.V.J.)" @default.
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- W2246142125 date "1961-01-01" @default.
- W2246142125 modified "2023-09-24" @default.
- W2246142125 title "CYTOCHEMICAL REACTIONS OF RIBONUCLEOPROTEIDS OF MITOCHONDRIA AND OF THE TIGROID BODY OF NERVE CELLS WITHIN THE FIRST MINUTES FOLLOWING $gamma$-IRRADIATION" @default.
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