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- W2246233898 abstract "Sixteen patients with metastatic nonseminomatous testicular cancer refractory to cisplatinum combination chemotherapy, were treated with epirubicin 100-120 mg/m2 q d 22. One partial remission lasting 6 months was achieved. Two additional patients had stabilisation of disease for 3 and 4 months. Median time to progression was 43 days. Myelosuppression was dose-limiting, with a WBC nadir of 1900/microliters. 4/30 cycles (13%) were associated with granulocytopenic fever. One patient developed a decline in cardiac ejection fraction without clinical signs of congestive heart failure. Epirubicin in this dosage and schedule has no major therapeutic activity in heavily pretreated non-seminomatous testicular cancer." @default.
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- W2246233898 date "1990-09-01" @default.
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- W2246233898 title "High dose epirubicin in refractory or relapsed non-seminomatous testicular cancer: A phase II study" @default.
- W2246233898 doi "https://doi.org/10.1093/oxfordjournals.annonc.a057778" @default.
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