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- W2246258650 abstract "The purpose of the rapport is to study the main steps of the pre-tumour changes of tissues under the protecting effect of some pigments from the group of carotenoids. To see the tumor development we tried to reproduce them in experimental animals with subcutaneous administrated dimethyl-benzanthracen (DMBA). We chose the following carotenoids pigments: cantaxanthin and rodoxanthin. For this experiment we used 20 mice, grouped in two lots. Group 1: 10 mice subcutaneous inoculated (s.c.) with 0,1 ml DMBA solution; orally they received, daily, 0,2 ml cantaxanthin (40 µg cantaxanthin /kgc/day). Group 2: 10 mice inoculated s.c. with 0,1 ml DMBA solution and they received orally, daily, 0,2 ml rodoxanthin (40 µg rodoxanthin /kgc). The pigments were dissolved in vegetal oil. There had been made 2 DMBA inoculations, at 1 month distance, in dorsal subcutaneous region. After 8 and 12 months from the first DMBA inoculation, some animals were sacrificed. There were realized necropsy and histopathology exams." @default.
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- W2246258650 date "2008-12-03" @default.
- W2246258650 modified "2023-10-18" @default.
- W2246258650 title "STUDY OF THE PROTECTOR EFFECT OF CAROTENOIDS, IN EXPERIMENTAL INDUCTED SARCOMAS" @default.
- W2246258650 doi "https://doi.org/10.15835/buasvmcn-vm:63:1-2:2554" @default.
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