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- W2247106149 abstract "We examined the genetic links between bladder control and cognitive development at three years of age in over 2500 twin pairs from the Twins' Early Development (TEDS) study. 30% of the population are reported as never dry throughout the night and 4% are reported as never dry throughout the day. Those reported as never dry throughout the night are .3 SD below the population mean on verbal and non-verbal cognitive ability. Those reported as never dry throughout the day are .9 SD below the population mean on both verbal and non-verbal scores (all p<.0001). Night bladder control accounts for 2% of the variance in both verbal and non-verbal scores, and day bladder control accounts for 4% of the variance in both verbal and non-verbal scores. Our published research so far shows moderate genetic influence on both verbal and non-verbal cognitive ability at three years, with a strong genetic link between them. We now find moderate heritability of nocturnal bladder control and high heritability of daytime bladder control. Furthermore, preliminary analysis shows genetic links between bladder control and cognitive development, suggesting a genetic component to overall developmental delay early in life, affecting cognitive development as well as other maturational processes." @default.
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- W2247106149 date "2000-08-07" @default.
- W2247106149 modified "2023-09-25" @default.
- W2247106149 title "Genetic links between bladder control and cognitive scores at three years of age: Exploring developmental delays in 2500 twins." @default.
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