FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2247139643> ?p ?o ?g. }

• W2247139643 endingPage "434" @default.
• W2247139643 startingPage "425" @default.
• W2247139643 abstract "Entamoeba histolytica is the causative agent of amoebiasis, a disease that produces dysentery as a result of the perforation of the large intestine. This parasite often invades other organs, primarily the liver, leading to an amoebic liver abscess (ALA), which can cause death. Metronidazole is the drug of choice for the treatment of ALA; however, it produces toxic side effects in patients. Lactoferrin (Lf) is a glycoprotein of the innate immune response that sequesters iron in the mucosae. Lf possesses immune-regulatory properties, such as antiinflammatory and antioxidant activities. Moreover, the microbicidal activity of apoLf, which lacks bound iron, has been shown. In this study, we evaluated the therapeutic effect of bovine Lf (bLf) against ALA in a model of hepatic amoebiasis in hamsters. Interestingly, hamsters treated intragastrically with Lf (2.5 mg/100 g mass) over a period of 8 days showed no clinical signs of disease and ALA was effectively decreased, with only 0.63% detectable lesion, compared with 63% in untreated animals. Furthermore, liver function and blood cells approached normal levels among those receiving bLf treatment. These results suggest that bLf may aid in the therapy of amoebiasis, likely without producing undesirable effects in patients." @default.
• W2247139643 created "2016-06-24" @default.
• W2247139643 creator A5039358774 @default.
• W2247139643 creator A5067269808 @default.
• W2247139643 creator A5077778360 @default.
• W2247139643 creator A5079718760 @default.
• W2247139643 creator A5087561417 @default.
• W2247139643 date "2012-06-01" @default.
• W2247139643 modified "2023-09-26" @default.
• W2247139643 title "Effect of bovine lactoferrin in a therapeutic hamster model of hepatic amoebiasis¹This article is part of a Special Issue entitled Lactoferrin and has undergone the Journal's usual peer review process." @default.
• W2247139643 cites W16631805 @default.
• W2247139643 cites W1808348270 @default.
• W2247139643 cites W1819961178 @default.
• W2247139643 cites W1950514687 @default.
• W2247139643 cites W1979521204 @default.
• W2247139643 cites W1995168920 @default.
• W2247139643 cites W1998434252 @default.
• W2247139643 cites W2004337051 @default.
• W2247139643 cites W2005528651 @default.
• W2247139643 cites W2006205749 @default.
• W2247139643 cites W2015490622 @default.
• W2247139643 cites W2021141349 @default.
• W2247139643 cites W2022948175 @default.
• W2247139643 cites W2052006138 @default.
• W2247139643 cites W2057682417 @default.
• W2247139643 cites W2061085356 @default.
• W2247139643 cites W2071818349 @default.
• W2247139643 cites W2077298382 @default.
• W2247139643 cites W2077752559 @default.
• W2247139643 cites W2084569396 @default.
• W2247139643 cites W2086578282 @default.
• W2247139643 cites W2094817926 @default.
• W2247139643 cites W2102173727 @default.
• W2247139643 cites W2106847587 @default.
• W2247139643 cites W2110250867 @default.
• W2247139643 cites W2112849118 @default.
• W2247139643 cites W2119227971 @default.
• W2247139643 cites W2123559285 @default.
• W2247139643 cites W2123845161 @default.
• W2247139643 cites W2124087884 @default.
• W2247139643 cites W2130616784 @default.
• W2247139643 cites W2131381352 @default.
• W2247139643 cites W2132501608 @default.
• W2247139643 cites W2144350481 @default.
• W2247139643 cites W2145329403 @default.
• W2247139643 cites W2145476821 @default.
• W2247139643 cites W2150336290 @default.
• W2247139643 cites W2151405634 @default.
• W2247139643 cites W2158710625 @default.
• W2247139643 cites W2169628708 @default.
• W2247139643 cites W4211257403 @default.
• W2247139643 cites W4231017639 @default.
• W2247139643 cites W4238989738 @default.
• W2247139643 doi "https://doi.org/10.1139/o11-084" @default.
• W2247139643 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22332957" @default.
• W2247139643 hasPublicationYear "2012" @default.
• W2247139643 type Work @default.
• W2247139643 sameAs 2247139643 @default.
• W2247139643 citedByCount "15" @default.
• W2247139643 countsByYear W22471396432014 @default.
• W2247139643 countsByYear W22471396432015 @default.
• W2247139643 countsByYear W22471396432016 @default.
• W2247139643 countsByYear W22471396432017 @default.
• W2247139643 countsByYear W22471396432019 @default.
• W2247139643 countsByYear W22471396432020 @default.
• W2247139643 countsByYear W22471396432022 @default.
• W2247139643 countsByYear W22471396432023 @default.
• W2247139643 crossrefType "journal-article" @default.
• W2247139643 hasAuthorship W2247139643A5039358774 @default.
• W2247139643 hasAuthorship W2247139643A5067269808 @default.
• W2247139643 hasAuthorship W2247139643A5077778360 @default.
• W2247139643 hasAuthorship W2247139643A5079718760 @default.
• W2247139643 hasAuthorship W2247139643A5087561417 @default.
• W2247139643 hasConcept C126322002 @default.
• W2247139643 hasConcept C136449434 @default.
• W2247139643 hasConcept C203014093 @default.
• W2247139643 hasConcept C2776867272 @default.
• W2247139643 hasConcept C2777396551 @default.
• W2247139643 hasConcept C2778455923 @default.
• W2247139643 hasConcept C2779170986 @default.
• W2247139643 hasConcept C2780708024 @default.
• W2247139643 hasConcept C2992208098 @default.
• W2247139643 hasConcept C501593827 @default.
• W2247139643 hasConcept C55493867 @default.
• W2247139643 hasConcept C71924100 @default.
• W2247139643 hasConcept C86803240 @default.
• W2247139643 hasConcept C8891405 @default.
• W2247139643 hasConcept C89423630 @default.
• W2247139643 hasConcept C90924648 @default.
• W2247139643 hasConceptScore W2247139643C126322002 @default.
• W2247139643 hasConceptScore W2247139643C136449434 @default.
• W2247139643 hasConceptScore W2247139643C203014093 @default.
• W2247139643 hasConceptScore W2247139643C2776867272 @default.
• W2247139643 hasConceptScore W2247139643C2777396551 @default.
• W2247139643 hasConceptScore W2247139643C2778455923 @default.
• W2247139643 hasConceptScore W2247139643C2779170986 @default.
• W2247139643 hasConceptScore W2247139643C2780708024 @default.
• W2247139643 hasConceptScore W2247139643C2992208098 @default.

• next