FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2247198812> ?p ?o ?g. }

• W2247198812 endingPage "13" @default.
• W2247198812 startingPage "4" @default.
• W2247198812 abstract "The efficacy and toxicity of high-dose chemotherapy with autologous bone marrow transplantation (ABMT) was studied in 32 patients with untreated limited small-cell bronchogenic carcinoma (SCBC). Ten patients received three courses of induction therapy consisting of vincristine (VCR) (1.5 mg X 2), ifosfamide (5 g/m2), and Adriamycin (Ad; Adria Laboratories, Columbus, Ohio) (60 mg/m2). Patients then received two courses of intensification therapy with cyclophosphamide (CYT) (4.5 g/m2), 4' demethyl-epipodophyllotoxin-d-D-ethylidene glucoside (VP-16-213) (600 mg/m2) and VCR (2 mg) with ABMT. Another 22 patients received induction therapy with VCR, CYT (600 mg/m2), Ad (50 mg/m2), and VP-16-213 (180 mg/m2). All 22 patients also received intensification therapy of the same dose of CYT (4.5 g/m2) and VP-16-213 (600 mg/m2). Nine patients also received high-dose methotrexate (MTX), four patients received Ad (40 to 60 mg/m2), and two patients received both Ad and MTX. After intensification, patients received elective prophylactic brain irradiation (3,000 rad) and chest irradiation (5,000 rad). After induction therapy, there were 13 (41%) complete remissions (CR) and 17 (53%) partial remissions (PR). After intensification therapy, there were 22 CRs (69%) and 10 PRs (31%). Median survival for all patients was 14 months (range, 5 to 59+). Of the 13 patients who received intensification therapy in CR, five remain disease free (DF), four for 4 years or longer. Of the nine patients to achieve CR with intensification, only one is DF. No patient died during intensification. In conclusion, intensification with high-dose chemotherapy can increase the CR rate, and this approach is most likely to show long-term benefits in patients with minimal disease (CR) at the beginning of intensification therapy." @default.
• W2247198812 created "2016-06-24" @default.
• W2247198812 creator A5004064839 @default.
• W2247198812 creator A5012851837 @default.
• W2247198812 creator A5021295987 @default.
• W2247198812 creator A5032191916 @default.
• W2247198812 creator A5033108697 @default.
• W2247198812 creator A5048531550 @default.
• W2247198812 creator A5052894313 @default.
• W2247198812 creator A5062931781 @default.
• W2247198812 creator A5063350015 @default.
• W2247198812 creator A5072786200 @default.
• W2247198812 date "1986-01-01" @default.
• W2247198812 modified "2023-10-01" @default.
• W2247198812 title "High-dose intensification therapy with autologous bone marrow support for limited small-cell bronchogenic carcinoma." @default.
• W2247198812 cites W149878195 @default.
• W2247198812 cites W169303988 @default.
• W2247198812 cites W1793154303 @default.
• W2247198812 cites W1916635100 @default.
• W2247198812 cites W1962075013 @default.
• W2247198812 cites W1974407877 @default.
• W2247198812 cites W1978895378 @default.
• W2247198812 cites W2011427246 @default.
• W2247198812 cites W2020877355 @default.
• W2247198812 cites W2026082132 @default.
• W2247198812 cites W2026810896 @default.
• W2247198812 cites W2046789782 @default.
• W2247198812 cites W2057336215 @default.
• W2247198812 cites W2060433518 @default.
• W2247198812 cites W2061653881 @default.
• W2247198812 cites W2074816774 @default.
• W2247198812 cites W2094666205 @default.
• W2247198812 cites W2098415065 @default.
• W2247198812 cites W2138324480 @default.
• W2247198812 cites W2339709756 @default.
• W2247198812 cites W2413770114 @default.
• W2247198812 cites W2417485617 @default.
• W2247198812 cites W2418513986 @default.
• W2247198812 cites W2419116497 @default.
• W2247198812 cites W2423635603 @default.
• W2247198812 cites W2437222413 @default.
• W2247198812 cites W2475237973 @default.
• W2247198812 cites W31189441 @default.
• W2247198812 cites W2494173086 @default.
• W2247198812 cites W2499220578 @default.
• W2247198812 cites W2502052647 @default.
• W2247198812 doi "https://doi.org/10.1200/jco.1986.4.1.4" @default.
• W2247198812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3510281" @default.
• W2247198812 hasPublicationYear "1986" @default.
• W2247198812 type Work @default.
• W2247198812 sameAs 2247198812 @default.
• W2247198812 citedByCount "79" @default.
• W2247198812 countsByYear W22471988122017 @default.
• W2247198812 crossrefType "journal-article" @default.
• W2247198812 hasAuthorship W2247198812A5004064839 @default.
• W2247198812 hasAuthorship W2247198812A5012851837 @default.
• W2247198812 hasAuthorship W2247198812A5021295987 @default.
• W2247198812 hasAuthorship W2247198812A5032191916 @default.
• W2247198812 hasAuthorship W2247198812A5033108697 @default.
• W2247198812 hasAuthorship W2247198812A5048531550 @default.
• W2247198812 hasAuthorship W2247198812A5052894313 @default.
• W2247198812 hasAuthorship W2247198812A5062931781 @default.
• W2247198812 hasAuthorship W2247198812A5063350015 @default.
• W2247198812 hasAuthorship W2247198812A5072786200 @default.
• W2247198812 hasConcept C126322002 @default.
• W2247198812 hasConcept C126894567 @default.
• W2247198812 hasConcept C141071460 @default.
• W2247198812 hasConcept C2776694085 @default.
• W2247198812 hasConcept C2776755627 @default.
• W2247198812 hasConcept C2777506904 @default.
• W2247198812 hasConcept C2778119113 @default.
• W2247198812 hasConcept C2779429289 @default.
• W2247198812 hasConcept C2781059491 @default.
• W2247198812 hasConcept C29730261 @default.
• W2247198812 hasConcept C509974204 @default.
• W2247198812 hasConcept C71924100 @default.
• W2247198812 hasConcept C90924648 @default.
• W2247198812 hasConceptScore W2247198812C126322002 @default.
• W2247198812 hasConceptScore W2247198812C126894567 @default.
• W2247198812 hasConceptScore W2247198812C141071460 @default.
• W2247198812 hasConceptScore W2247198812C2776694085 @default.
• W2247198812 hasConceptScore W2247198812C2776755627 @default.
• W2247198812 hasConceptScore W2247198812C2777506904 @default.
• W2247198812 hasConceptScore W2247198812C2778119113 @default.
• W2247198812 hasConceptScore W2247198812C2779429289 @default.
• W2247198812 hasConceptScore W2247198812C2781059491 @default.
• W2247198812 hasConceptScore W2247198812C29730261 @default.
• W2247198812 hasConceptScore W2247198812C509974204 @default.
• W2247198812 hasConceptScore W2247198812C71924100 @default.
• W2247198812 hasConceptScore W2247198812C90924648 @default.
• W2247198812 hasIssue "1" @default.
• W2247198812 hasLocation W22471988121 @default.
• W2247198812 hasLocation W22471988122 @default.
• W2247198812 hasOpenAccess W2247198812 @default.
• W2247198812 hasPrimaryLocation W22471988121 @default.
• W2247198812 hasRelatedWork W2008641803 @default.
• W2247198812 hasRelatedWork W2013808387 @default.
• W2247198812 hasRelatedWork W2019647702 @default.

• next