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- W2247246016 abstract "A direct structural identification, and quantitative assessment below the 50 nmol/ml level, of the full pattern of renally excreted metabolites is made possible by 13C NMR measurements of untreated urine samples when stable isotope-labelled (13C) drug analogues are administered to humans. The full potential of the new ex vivo NMR approach is exemplified by a study, for a group of volunteers, of S-carboxymethyl-L-cysteine metabolism. The metabolic sulphoxidation pathway of S-carboxymethyl-L-cysteine in man, accepted so far, needs to be profoundly revised on the basis of the 13C NMR results." @default.
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- W2247246016 date "1990-12-01" @default.
- W2247246016 modified "2023-09-27" @default.
- W2247246016 title "Tracing the Human Metabolism of Stable Isotope-Labelled Drugs by ex vivo NM R Spectroscopy A Revision of S-Carboxymethyl-ʟ-cysteine Biotransformation" @default.
- W2247246016 doi "https://doi.org/10.1515/znc-1990-11-1215" @default.
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