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- W2247302018 abstract "The eyes of 120 rabbits, 8 to 12 weeks of age, received radiation doses of 0, 200, 600, 1000 r from a 1-Mev x-ray machine. The x-ray dose was delivered either to the whole eye or to a portion of the eye. All animals received a biomicroscopic examination before irradiation and at 6-month intervals thereafter until death or sacrifice intervened. The colony of 120 rabbits was divided into 6 groups according to a balanced incomplete block arrangement designed statistically for maximum information. Animals were sacrificed, 4 at a time, at 6-month interval until each of the 6 groups was depleted. The relation be seen ionizing radiation exposure and aging is given in terms of physical data involving the mass, density, hardness, and light transmission of the rabbit lens, and in terms of the clinical findings. The data indicate that changes in the physical properties of the lens seem dependent primarily upon age, whereas clinical findings seem most affected by radration dose and method of exposure. Chemical changes in the lens proteins were detected after exposure to 25 r. In general, these data do not support the hypothesis that there is a well-defined relation between radiation damage and aging in themore » rabbit lens. (auth)« less" @default.
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- W2247302018 date "1964-10-31" @default.
- W2247302018 modified "2023-09-23" @default.
- W2247302018 title "A STUDY OF THE COMPARATIVE EFFECTS OF IONIZING RADIATION AND AGING ON THE MAMMALIAN LENS OF THE EYE. Final Scientific Report" @default.
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