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- W2247397314 abstract "Background: Considering the severe hazardous influences of Lead (Pb2+) on iron-related diseases, this study was carried out to evaluate the effects of Pb2+ on the serum parameters associated with iron metabolism. Materials and Methods: In this experimental study, male Wistar rats weighing 200–250 g were treated with Pb2+ for the short and long period of time. The animals received daily intraperitoneal injection of 100 mg Pb 2+ kg−1 body weight (BW) for 5 days and 4 mg Pb2+ kg−1 BW for 30 and 45 days, respectively. Results: The results showed that when animals were treated with both low and high concentrations of Pb 2+, the serum iron concentrations decreased markedly by 23.2%, 32.8%, and 39.9 % after 5, 30 and 45 days, respectively, while the sera TIBC and transferrin concentrations increased significantly (P Conclusion: The results suggest that the changes in serum parameters associated with iron metabolism may play an important role in producing iron-related diseases." @default.
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- W2247397314 date "2013-01-01" @default.
- W2247397314 modified "2023-09-23" @default.
- W2247397314 title "Evaluating the changes in serum parameters associated with iron metabolism in male rat exposed to Lead" @default.
- W2247397314 hasPublicationYear "2013" @default.
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