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- W2247405718 abstract "20001 Background: The high recurrence and mortality rates associated with NM are generally attributed to its advanced thickness at presentation; nevertheless, we and others have recently reported that NM may have distinct biologic characteristics independent of thickness. Here, we examine the differences in clinical behavior of NM compared to SSM at NYU, a tertiary referral center, over three decades. Methods: 1,684 melanoma patients (pts) prospectively enrolled were studied. 1,143 pts were diagnosed 1972–1982 (median thickness 1.3mm; 793 (69%) SSM, 126 (11%) NM, and 224 (20%) other). 541 pts were diagnosed 2002-present (median thickness 0.9mm; 299 (55%) SSM, 125 (23%) NM, 117 (22%) other). Differences between the features of NM and SSM within each time period as well as changes over time were analyzed using the t-test, Wilcoxon rank-sum test, or chi-square test, as appropriate. Results: Median age at diagnosis of NM increased from 51 years of age in 1972–1982 to 63 years of age in the current time period..." @default.
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- W2247405718 date "2008-05-20" @default.
- W2247405718 modified "2023-09-26" @default.
- W2247405718 title "Different clinical behavior of nodular melanoma (NM) compared to superficial spreading melanoma (SSM) at New York University from 1972 to present" @default.
- W2247405718 doi "https://doi.org/10.1200/jco.2008.26.15_suppl.20001" @default.
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