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- W2247484578 abstract "The agglutinin titres of tetanus antitoxins tested with preserved sheep cells sensitized with tetanus toxoid have been found to be inversely proportional to the cell concentration used.The agglutinin titres per international unit of antitoxin were widely different among various electrophoretically separated globulin fractions of tetanus antitoxin. There were smaller differences between the agglutinating capacity of γ-globulin fractions of sera from different horses.With haemagglutination inhibition tests there was always a relative increase in test dose between the LA and LA/100 level of test. This relative increase was greatest where the sensitivity of the cell suspensions was high.Increased suspension sensitivity may be the result of treatment of cells with greater quantities of sensitizing antigen or of reduction in the concentration of sensitized cells in the suspension.A greater volume of serum was required to give a standard end point, when mixed with a test dose (LA) of toxin, if the mixtures were allowed to stand for increasing periods of time. These observations have been discussed." @default.
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- W2247484578 date "1959-04-01" @default.
- W2247484578 modified "2023-10-18" @default.
- W2247484578 title "Factors influencing haemagglutination tests with tetanux antitoxin." @default.
- W2247484578 cites W2141676108 @default.
- W2247484578 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1423941" @default.
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