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- W2247609177 abstract "Sudden death appears in 8-17% of epilepsy patients non-responding to antiepileptic therapy. Some studies suggest that the most common cause of death is seizure-related cardiac arrhythmia.To analyze the alteration of the heart rate six hours before and after the seizures.Eighteen patients suffering from focal epilepsy were examined before epilepsy surgery. Video-EEG-ECG was carried out for 2-10 days, and 32 seizures were registered. Analysis of the heart rate was based on the 5-minute-long epochs of the ECGs taken at the 5-10-15-30th minutes and at the 1-3-6th hours before and after seizures.The heart rate increases (from an average of 69 beats/min to 92 beats/min, p<0.001) immediately after seizures, though significantly higher heart rate was observed 3 hours after seizures. There were no patients with severe peri-ictal bradycardia. In one of our patients, ectopic cardiac rhythm occurred after a generalized tonic-clonic seizure.We can conclude that the sympathetic activity increases while the parasympathetic activity decreases after seizures. The observed alterations lasted for a long time and predict fatal arrhythmias. These suggest that sudden death in epilepsy can be induced by cardiac arrhythmias connected with epileptic seizures." @default.
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- W2247609177 date "2008-05-30" @default.
- W2247609177 modified "2023-10-17" @default.
- W2247609177 title "[Effect of epileptic seizures on the heart rate]." @default.
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