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- W2247691201 abstract "Introduction : Multidrug-resistant tuberculosis (MDRTB) is a major problem in TB control program globally. The incidence of MDRTB in Malaysia is increasing over last few years. The outcome is worse compared to pan susceptible TB. Objectives : The objectives are to determine the demographic characteristics and describe the outcomes of MDRTB patients in our center. Methods : A retrospective study of MDRTB diagnosed in Institute of Respiratory Medicine, Kuala Lumpur. Patients were identified based on sputum mycobacterium culture and sensitivity records from June 2007 to June 2013 and data were collected from patients9 notes. Results: Total numbers of MDRTB cases diagnosed during the periods were 87. The median age was 37 (IQR 22), ranges from 14 to 61 years old. Two third (66.7%) of cases were male. 43 (49.4%) were Malaysian and 44 (50.6%) foreign born. Majority of patients were Myanmar9s (36.8%), followed by the Malays (29.9%). The majority of MDRTB cases were acquired (65.5%). All patients received second line therapy. Out of 87 cases, 34.5% cured, 21.8% defaulted treatment, 16.1% transferred out, 8.1% died and 19.5% on treatment. We found significant correlation between severity of radiological findings, disease complications and duration of symptoms with the patients9 outcome (P Conclusion : Our result demonstrated that the majority of MDRTB cases were acquired. The cured rate in studied cohort was 34.5%. Advanced radiological findings, disease complications and prolonged symptoms were associated with poor outcome." @default.
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- W2247691201 date "2014-09-01" @default.
- W2247691201 modified "2023-09-28" @default.
- W2247691201 title "Analysis of multidrug-resistant tuberculosis" @default.
- W2247691201 hasPublicationYear "2014" @default.
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