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- W2247702188 abstract "The primary structure of a polypeptide can be predicted by translating its mRNA sequence according to the 'universal' genetic code. Yet, recent evidence has shown that a number of nonstandard translational events may occur in cells, generating microheterogeneity in the translation product at the amino acid level. Such events can be programmed by sequences within the mRNA, or may just represent nonprogrammed errors that occur during translation as a result of depletion of specific aminoacyl-tRNAs. The potential occurrence of such errors must be considered and steps taken both to identify and eliminate them when expression strategies are being developed for producing recombinant proteins for human therapeutic use." @default.
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- W2247702188 date "1993-12-01" @default.
- W2247702188 modified "2023-09-27" @default.
- W2247702188 title "New insights into messenger-rna decoding - implications for heterologous protein-synthesis" @default.
- W2247702188 hasPublicationYear "1993" @default.
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