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• W2247887587 endingPage "2162" @default.
• W2247887587 startingPage "2155" @default.
• W2247887587 abstract "Cancer and its treatment may affect cognitive function through a number of direct and indirect pathways including inflammation, lipid metabolism, vascular damage, and changes in the blood-brain barrier. While short-term treatment-related cognitive changes are well recognized, only limited research is available in older, long-term survivors of cancer.Using NHANES data from 1999 to 2002, 408 cancer survivors and 2639 non-cancer participants aged 60 years old and above were identified. Cognitive function of these groups were compared using the Digit Symbol Substitution Test (DSST) and self-reported problems with memory or confusion.After adjustment for covariates, cancer survivors scored, on average, 1.99 points lower on the DSST compared to non-cancer survivors (-1.99, 95 % CI -3.94, -0.05). Cancer survivors also had 17 % higher odds of self-reporting problems with memory or confusion (OR 1.17, 95 % CI 0.89, 1.53).In this nationally representative sample of older US adults, cancer survivors had lower DSST scores than non-survivors and had more self-reported problems with memory or confusion." @default.
• W2247887587 created "2016-06-24" @default.
• W2247887587 creator A5002897454 @default.
• W2247887587 creator A5078837203 @default.
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• W2247887587 date "2015-11-09" @default.
• W2247887587 modified "2023-10-14" @default.
• W2247887587 title "Cognitive function in cancer survivors: analysis of the 1999–2002 National Health and Nutrition Examination Survey" @default.
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• W2247887587 doi "https://doi.org/10.1007/s00520-015-2992-2" @default.
• W2247887587 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4933958" @default.
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• W2247887587 hasPublicationYear "2015" @default.
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