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- W2248010518 abstract "Slowing down DNA translocation and achieving single-nucleobase resolution are major issues for the realization of nanopore-based whole-genome sequencing [1]. Besides approaches that can directly target the forces acting on a DNA molecule [2,3], chemical modifications of the nanopore interior represent a promising method to both lower the translocation speed and simultaneously improve sensitivity. Complex functionalization of nanopore-embedded gold electrodes with one [4] or two types of molecules [5] has been theoretically explored in this regard, but it may be too difficult for practical implementation. Graphene nanopores or nanogaps might be better suited since their fabrication process would likely introduce simple edge-functionalization in the form of H-atoms or OH-groups, saturating the dangling bonds which resulted from cutting the hexagonal carbon network." @default.
- W2248010518 created "2016-06-24" @default.
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- W2248010518 date "2013-03-21" @default.
- W2248010518 modified "2023-09-23" @default.
- W2248010518 title "Edge-functionalization aspects in DNA sequencing with graphene nano-electrodes" @default.
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