Matches in SemOpenAlex for { <https://semopenalex.org/work/W2248052256> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2248052256 abstract "Since pentobarbital anesthesia is known to attenuate certain autonomic reflexes, we tested whether pentobarbital would suppress both basal and stimulated levels of plasma catecholamines and whether a large stimulus might counterbalance this suspected suppression. In untrained dogs, sampled by venipuncture, pentobarbital (30 mg/kg iv) decreased the plasma concentration of epinephrine (E) from 146 +/- 9 to 38 +/- 8 (SE) pg/ml (n = 46) and norepinephrine (NE) from 276 +/- 13 to 91 +/- 10 pg/ml (both P less than 0.0005), suggesting that barbiturate anesthesia suppresses sympathetic outflow in these mildly stressed animals. Pentobarbital also had a marked suppressive effect on the lower baseline catecholamines (E, 84 +/- 14 pg/ml; NE, 118 +/- 10 pg/ml; n = 6) of trained, chronically catheterized dogs, suggesting that it was capable of suppressing resting sympathetic outflow as well. To determine whether pentobarbital anesthesia also suppressed reflex activation of the sympathetic nervous system, the plasma catecholamine response to the neuroglucopenic agent, 2-deoxy-D-glucose (2-DG), was measured in conscious and in pentobarbital-anesthetized dogs. In conscious dogs, the administration of 2-DG (100 mg/kg iv) doubled the base-line plasma concentration of E and NE 30 min after the 2-DG injection. In contrast, the administration of 2-DG (100 mg/kg iv) to pentobarbital-anesthetized dogs produced no significant increase of either plasma catecholamine, suggesting marked suppression of this sympathetic reflex.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2248052256 created "2016-06-24" @default.
- W2248052256 creator A5010597749 @default.
- W2248052256 creator A5035495914 @default.
- W2248052256 creator A5041909166 @default.
- W2248052256 creator A5061642453 @default.
- W2248052256 creator A5072056585 @default.
- W2248052256 date "1984-11-01" @default.
- W2248052256 modified "2023-09-24" @default.
- W2248052256 title "Pentobarbital anesthesia suppresses basal and 2-deoxy-D-glucose-stimulated plasma catecholamines" @default.
- W2248052256 cites W1772768232 @default.
- W2248052256 cites W1895952682 @default.
- W2248052256 cites W1931850494 @default.
- W2248052256 cites W1963989474 @default.
- W2248052256 cites W2017482634 @default.
- W2248052256 cites W2023896691 @default.
- W2248052256 cites W2071502521 @default.
- W2248052256 cites W2089831182 @default.
- W2248052256 cites W2110298989 @default.
- W2248052256 cites W2258246535 @default.
- W2248052256 cites W2314076351 @default.
- W2248052256 cites W2340425608 @default.
- W2248052256 cites W89324897 @default.
- W2248052256 doi "https://doi.org/10.1152/ajpregu.1984.247.5.r905" @default.
- W2248052256 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6496774" @default.
- W2248052256 hasPublicationYear "1984" @default.
- W2248052256 type Work @default.
- W2248052256 sameAs 2248052256 @default.
- W2248052256 citedByCount "20" @default.
- W2248052256 countsByYear W22480522562016 @default.
- W2248052256 countsByYear W22480522562021 @default.
- W2248052256 crossrefType "journal-article" @default.
- W2248052256 hasAuthorship W2248052256A5010597749 @default.
- W2248052256 hasAuthorship W2248052256A5035495914 @default.
- W2248052256 hasAuthorship W2248052256A5041909166 @default.
- W2248052256 hasAuthorship W2248052256A5061642453 @default.
- W2248052256 hasAuthorship W2248052256A5072056585 @default.
- W2248052256 hasConcept C126322002 @default.
- W2248052256 hasConcept C134018914 @default.
- W2248052256 hasConcept C185592680 @default.
- W2248052256 hasConcept C2775859304 @default.
- W2248052256 hasConcept C2775894120 @default.
- W2248052256 hasConcept C2776533406 @default.
- W2248052256 hasConcept C2776755955 @default.
- W2248052256 hasConcept C2778514916 @default.
- W2248052256 hasConcept C2780077838 @default.
- W2248052256 hasConcept C42219234 @default.
- W2248052256 hasConcept C513476851 @default.
- W2248052256 hasConcept C71924100 @default.
- W2248052256 hasConcept C83974742 @default.
- W2248052256 hasConcept C84393581 @default.
- W2248052256 hasConceptScore W2248052256C126322002 @default.
- W2248052256 hasConceptScore W2248052256C134018914 @default.
- W2248052256 hasConceptScore W2248052256C185592680 @default.
- W2248052256 hasConceptScore W2248052256C2775859304 @default.
- W2248052256 hasConceptScore W2248052256C2775894120 @default.
- W2248052256 hasConceptScore W2248052256C2776533406 @default.
- W2248052256 hasConceptScore W2248052256C2776755955 @default.
- W2248052256 hasConceptScore W2248052256C2778514916 @default.
- W2248052256 hasConceptScore W2248052256C2780077838 @default.
- W2248052256 hasConceptScore W2248052256C42219234 @default.
- W2248052256 hasConceptScore W2248052256C513476851 @default.
- W2248052256 hasConceptScore W2248052256C71924100 @default.
- W2248052256 hasConceptScore W2248052256C83974742 @default.
- W2248052256 hasConceptScore W2248052256C84393581 @default.
- W2248052256 hasLocation W22480522561 @default.
- W2248052256 hasLocation W22480522562 @default.
- W2248052256 hasOpenAccess W2248052256 @default.
- W2248052256 hasPrimaryLocation W22480522561 @default.
- W2248052256 hasRelatedWork W1978175539 @default.
- W2248052256 hasRelatedWork W2024482129 @default.
- W2248052256 hasRelatedWork W2038512896 @default.
- W2248052256 hasRelatedWork W2044985824 @default.
- W2248052256 hasRelatedWork W2046261096 @default.
- W2248052256 hasRelatedWork W2060199686 @default.
- W2248052256 hasRelatedWork W2076974163 @default.
- W2248052256 hasRelatedWork W2101285485 @default.
- W2248052256 hasRelatedWork W2160913746 @default.
- W2248052256 hasRelatedWork W2180683357 @default.
- W2248052256 isParatext "false" @default.
- W2248052256 isRetracted "false" @default.
- W2248052256 magId "2248052256" @default.
- W2248052256 workType "article" @default.