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- W2248511069 abstract "In a high percentage of old age patients with lipid metabolism disturbances, who were treated with digoxin, subtherapeutic concentrations of this drug in the serum were noted. The analysed group consisted of 34 old age patients, 12 with hypercholesterolemia and 22 with mixed hyperlipidemia. Patients were treated with digoxin in the constant dose of 0,25 mg/day. The blood for analysis was collected in the steady-state period. Serum digoxin subtherapeutic concentrations were noted in 38,2 % of the investigated patients, therapeutic concentrations were noted in 42,2 % of these patients and concentrations above the limit range were noted in 17,6 % of patients. Subtherapeutic digoxin concentrations were observed most frequently in patients with hypercholesterolemia." @default.
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- W2248511069 date "1999-10-18" @default.
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- W2248511069 title "Hyperlipidemia and serum digoxin concentration in old patients" @default.
- W2248511069 hasPublicationYear "1999" @default.
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