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• W2248514018 abstract "On the basis of the potent antiviral activity of acyclovir and ganciclovir, selenoacyclovir (2a) and selenoganciclovir (2b) were designed based on bioisoteric rationale and synthesized via the diselenide 7 as the key intermediate. Compound 2a exhibited potent anti-HSV-1 and -2 activities while 2b exerted moderate anti-HCMV activity, indicating that these nucleosides can serve as a novel template for the development of new antiviral agents." @default.
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• W2248514018 date "2015-10-23" @default.
• W2248514018 modified "2023-10-06" @default.
• W2248514018 title "Selenoacyclovir and Selenoganciclovir: Discovery of a New Template for Antiviral Agents" @default.
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• W2248514018 doi "https://doi.org/10.1021/acs.jmedchem.5b00804" @default.
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