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- W2248705494 abstract "There is almost universal agreement that rheumatic fever and rheumatic heart disease are always preceded by infection with group A beta-hemolytic streptococcus. In most developed countries, the reported incidence of both rheumatic fever and rheumatic heart disease has declined drastically. The fact that the onset of this decline preceded the advent of antibiotics indicates that factors other than streptococcal infection must play a role in the pathogenesis of this condition. Despite worldwide research, the factors causing a high prevalence of rheumatic heart disease in any community remain uncertain. It is favored that socioeconomic factors are important; hence, the continued high prevalence of rheumatic heart disease in Third World countries. In 1978, Padmavati [1] concluded that “prophylaxis was hardly worthwhile” in patients encountered for the first time with a late stage of rheumatic heart disease. Such cases comprised 75% of those considered for a secondary prophylaxis program in India between 1968 and 1974. While it is now rare to encounter White patients under the age of 20 years with rheumatic heart disease, the clinical experience of those involved with the diagnosis and treatment of Black South African patients is that rheumatic heart disease remains prevalent and continues to affect young children. In 1972 a survey of 12 050 Black schoolchildren in the Johannesburg area [2] detected an overall prevalence rate for rheumatic heart disease of 6.9/1000, with a peak rate of 19.2/1000 in children aged about 15–18 years.KeywordsMitral ValveMitral RegurgitationInfective EndocarditisRheumatic FeverRheumatic ActivityThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W2248705494 date "1991-01-01" @default.
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- W2248705494 title "Mechanisms and Management of Heart Failure in Active Rheumatic Carditis" @default.
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- W2248705494 doi "https://doi.org/10.1007/978-3-642-58231-8_15" @default.
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