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- W2249820021 abstract "Background: The Australian Schizophrenia Research Bank (ASRB) was established in 2007 to collect linked clinical, cognitive, neuroimaging and genetic data in people with schizophrenia and matched controls. The ASRB is the first of its kind developed in Australia. Demographic, clinical and neurological data is presented for the first 550 participants with schizophrenia. Methods: Participants were assessed using a comprehensive assessment battery that consists of socio-demographic questions including medical and family history, neurological evaluation (NES), neuropsychological assessment and cognitive performance measures (WTAR, WASI, RBANS, LNS, COWAT), a diagnostic interview that includes drug and alcohol history (DIP, Castle et al, 2006) to confirm diagnosis, ratings for negative symptoms (SANS), general functioning (GAF), and questionnaires of childhood adversity, personality disorder (IPDE) and psychosis proneness (SPQ). Results: A sample of 550 people with schizophrenia (mean age = 39.66 years; SD = 10.98) and 250 healthy controls (mean International Congress on Schizophrenia Research 54 age = 37.37 years; SD = 13.14) were compared across measures. The schizophrenia sample had a higher proportion of males (cases 16.80%; controls 46.40%), fewer living in married or de facto relationships (cases 15.80%; controls 53.60%) and fewer years of education (cases 12.93, SD = 2.91; controls 15.13, SD = 3.14). Schizophrenia participants also had lower premorbid IQ (cases 103.17, SD = 13.17; controls 111.83, SD = 8.76), current IQ (cases 102.29, SD = 15.62; controls 118.24, SD = 10.20) and RBANS total score (cases 82.55, SD = 15.59; controls 96.24, SD = 15.88), consistent with performance reported previously for Australian samples (Loughland et al, 2007). Conclusion: These findings are consistent with those reported previously in the Australian Low Prevalence Disorders Study (Castle, 1999), suggesting the ASRB sample is broadly representative of people with schizophrenia living in Australia. The ASRB is a unique schizophrenia resource that is accessible to approved national and international researchers." @default.
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- W2249820021 date "2011-01-01" @default.
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- W2249820021 title "The Australian schizophrenia research bank (ASRB): The first 550 schizophrenia sample profile" @default.
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