FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2249830920> ?p ?o ?g. }

• W2249830920 endingPage "946" @default.
• W2249830920 startingPage "945" @default.
• W2249830920 abstract "Editor—Postoperative troponin as a marker of acute myocardial injury after noncardiac surgery (MINS) has been shown to predict clinical outcome in several studies.1Devereaux PJ Chan MT Alonso-Coello P et al.Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery.JAMA. 2012; 307: 2295-2304Crossref PubMed Scopus (721) Google Scholar, 2van Waes JA Nathoe HM de Graaff JC et al.Myocardial injury after noncardiac surgery and its association with short-term mortality.Circulation. 2013; 127: 2264-2271Crossref PubMed Scopus (224) Google Scholar, 3Nagele P Brown F Gage BF et al.High-sensitivity cardiac troponin T in prediction and diagnosis of myocardial infarction and long-term mortality after noncardiac surgery.Am Heart J. 2013; 166: 325-332Abstract Full Text Full Text PDF PubMed Scopus (118) Google Scholar, 4Noordzij PG van Geffen O Dijkstra IM et al.High-sensitive cardiac troponin T measurements in prediction of non-cardiac complications after major abdominal surgery.Br J Anaesth. 2015; 114: 909-918Abstract Full Text Full Text PDF PubMed Scopus (63) Google Scholar To date, current guidelines recommend that assessment of troponin after noncardiac surgery might be considered in high-risk patients.5Kristensen SD Knuuti J Saraste A et al.ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery: cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of Anaesthesiology (ESA).Eur Heart J. 2014; 35: 2383-2431Crossref PubMed Scopus (144) Google Scholar, 6Fleisher LA Fleischmann KE Auerbach AD et al.2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.Circulation. 2014; 130: 2215-2245Crossref PubMed Scopus (450) Google Scholar However, they do not specify which patients have to be considered at high-risk in this context, as the relative contribution of different risk factors in affecting the probability of MINS is still unclear. A better knowledge of the determinants of MINS could be useful to target the clinical choice of measuring troponin concentrations in the early postoperative period. We therefore retrospectively investigated the predictors of postoperative troponin I elevation, among consecutive patients admitted to the recovery room (RR) of our Institution, after noncardiac surgery between January 2011 and March 2015. We considered for inclusion all patients for whom at least one troponin measurement was obtained during the stay in the RR. According to RR protocols,7Conti D Ballo P Buoncristiano U et al.Clinical utility of an undersized nurse-operated recovery room in the postoperative course: results from an Italian community setting.J Perianesth Nurs. 2014; 29: 185-190Abstract Full Text Full Text PDF PubMed Scopus (6) Google Scholar postoperative troponin measurement was performed in the presence of at least one of the following complications: signs or symptoms suggestive of myocardial ischaemia; electrocardiographic or echocardiographic changes suggestive of ischaemic origin; persistent haemodynamic instability; sustained arrhythmias. In case of abnormal troponin concentrations, serial measurements were performed. A total of 277 subjects, representing 6.4% of all patients admitted to our RR after noncardiac surgery during the study period, entered the study population. Among them, at least one abnormal troponin concentration (normal value <0.06 ng ml−1) suggestive of MINS was found in 21 patients (group 1), whereas the remaining 256 showed concentrations under this cut-off (group 2). The main characteristics of the study groups are shown in Table 1. Patients in group one were older, more often diabetic, had a lower Visual Analogue Score, and showed larger prevalence of urgent intervention. There were no differences in other variables, including coronary artery disease, previous heart failure hospitalization, ASA score, type of surgery, need of general anaesthesia, and prevalence of comorbidities. When variables with P<0.10 at univariable logistic regression were tested by stepwise multivariable analysis, only age (OR 1.04[1.02–1.07], P=0.013) and urgent surgery (1.23[1.03–1.45], P=0.032) independently predicted MINS.Table 1Main clinical characteristics of the study groups VAS, Visual Analogue ScaleGroup 1Group 2P valueAge (yr)81.6 (15.7)76.0 (11.6)0.033Female gender (%)14 (63.6%)122 (47.7%)0.15Systemic hypertension (%)15 (68.2%)151 (59.0%)0.71Diabetes mellitus (%)10 (45.5%)63 (24.6%)0.033Coronary artery disease (%)4 (18.2%)54 (21.1%)0.80Previous heart failure hospitalization (%)1 (4.5%)19 (7.4%)0.98History of atrial fibrillation (%)6 (27.3%)53 (20.7%)0.59Previous PM implantation (%)–19 (7.4%)0.25Chronic kidney disease (%)4 (18.2%)26 (10.2%)0.27Previous stroke (%)–16 (6.3%)0.38Peripheral artery disease (%)2 (9.1%)13 (5.1%)0.62ASA score3.0 (0.8)2.8 (0.6)0.20General anaesthesia (%)12 (54.5%)141 (55.0%)0.99Type of surgery (%)0.39General9 (40.9%)75 (29.3%)Traumatological8 (36.4%)78 (30.5%)Urologic3 (13.6%)41 (16.0%)Gynecologic–24 (9.4%)Orthopaedic–18 (7.0%)Other1 (4.5%)20 (7.8%)Urgent intervention10 (45.5%)60 (23.4%)0.022Body temperature at admission (°C)35.6 (0.8)35.6 (0.7)0.91VAS at admission0 [0–0.75]0 [0–2.75]0.035Body temperature at discharge (°C)36.5 (0.7)36.3 (0.4)0.20VAS at discharge0 [0–1]1 [0–1]0.046 Open table in a new tab This study explored the predictors of MINS in a real-world population of patients admitted to a RR after noncardiac surgery. The role of MINS as an early marker of adverse outcome after noncardiac surgery was established by two large trials, showing an independent association with 30-day mortality.1Devereaux PJ Chan MT Alonso-Coello P et al.Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery.JAMA. 2012; 307: 2295-2304Crossref PubMed Scopus (721) Google Scholar, 2van Waes JA Nathoe HM de Graaff JC et al.Myocardial injury after noncardiac surgery and its association with short-term mortality.Circulation. 2013; 127: 2264-2271Crossref PubMed Scopus (224) Google Scholar Another recent analysis found that MINS predicted non-cardiac 30-day events in a population submitted to major abdominal surgery,4Noordzij PG van Geffen O Dijkstra IM et al.High-sensitive cardiac troponin T measurements in prediction of non-cardiac complications after major abdominal surgery.Br J Anaesth. 2015; 114: 909-918Abstract Full Text Full Text PDF PubMed Scopus (63) Google Scholar leading to the apparently paradoxical evidence that a marker of myocardial injury can predict postoperative non-cardiac complications, rather than cardiac ones.8Landesberg G Jaffe AS ‘Paradox’ of troponin elevations after non-cardiac surgery.Br J Anaesth. 2015; 114: 863-865Abstract Full Text Full Text PDF PubMed Scopus (19) Google Scholar Nonetheless, according to current guidelines, postoperative troponin screening in patients without signs or symptoms suggestive of myocardial ischaemia might be considered only in high-risk patients.5Kristensen SD Knuuti J Saraste A et al.ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management: The Joint Task Force on non-cardiac surgery: cardiovascular assessment and management of the European Society of Cardiology (ESC) and the European Society of Anaesthesiology (ESA).Eur Heart J. 2014; 35: 2383-2431Crossref PubMed Scopus (144) Google Scholar, 6Fleisher LA Fleischmann KE Auerbach AD et al.2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.Circulation. 2014; 130: 2215-2245Crossref PubMed Scopus (450) Google Scholar In our population, only older age and urgent surgery independently predicted MINS. The finding that age is a predictor of MINS is not surprising, considering the association between ageing and coronary artery disease,9Boutouyrie P Arterial ageing and coronary artery disease: physiopathological and epidemiological data.Arch Mal Coeur Vaiss. 2006; 99: 19-24PubMed Google Scholar, 10Odden MC Coxson PG Moran A et al.The impact of the aging population on coronary heart disease in the United States.Am J Med. 2011; 124: 827-833Abstract Full Text Full Text PDF PubMed Scopus (144) Google Scholar but may be clinically interesting because the mean age of the population who comes to surgery is continuously increasing.11Neuman MD Bosk CL The redefinition of aging in American surgery.Milbank Q. 2013; 91: 288-315Crossref PubMed Scopus (31) Google Scholar, 12Guarracino F Baldassarri R Priebe HJ Revised ESC/ESA Guidelines on non-cardiac surgery: cardiovascular assessment and management. Implications for preoperative clinical evaluation.Minerva Anestesiol. 2015; 81: 226-233PubMed Google Scholar On the other hand, the association between MINS and urgent surgery agrees with the well known increased risk of complications of non-elective interventions.13van Zaane B van Klei WA Buhre WF et al.European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology. Nonelective surgery at night and in-hospital mortality: Prospective observational data from the European Surgical Outcomes Study.Eur J Anaesthesiol. 2015; 32: 477-485Crossref PubMed Scopus (22) Google Scholar, 14Hietala P Strandberg M Kiviniemi T Strandberg N Airaksinen KE Usefulness of troponin T to predict short-term and long-term mortality in patients after hip fracture.Am J Cardiol. 2014; 114: 193-197Abstract Full Text Full Text PDF PubMed Scopus (49) Google Scholar This analysis only reflects a real-world retrospective experience. Also, some confounders such as preoperative creatinine and troponin concentrations were not available. Although the results of this pilot study require validation in larger, prospective analyses, our findings suggest that age and urgency should be carefully considered to identify high-risk patients, when evaluating the indication for postoperative troponin measurement after noncardiac surgery. None declared. Transfemoral aortic valve replacement: does anaesthesia make the difference?British Journal of AnaesthesiaVol. 116Issue 1PreviewTranscatheter aortic valve implantations (TAVI) have been introduced and further developed as a last therapeutic option in patients with severe aortic stenosis who are – because of severe co-morbidity - not suitable for open-heart operations. Different approaches for aortic valve implantation are nowadays routinely performed: transapical, transaortic and transfemoral placement of the aortic valve.1 Full-Text PDF Open Archive" @default.
• W2249830920 created "2016-06-24" @default.
• W2249830920 creator A5013736747 @default.
• W2249830920 creator A5032578992 @default.
• W2249830920 creator A5045045289 @default.
• W2249830920 creator A5080363463 @default.
• W2249830920 date "2015-12-01" @default.
• W2249830920 modified "2023-09-27" @default.
• W2249830920 title "Predictors of early postoperative troponin increase after noncardiac surgery: a pilot study in a real-world population admitted to the recovery room" @default.
• W2249830920 cites W1995076226 @default.
• W2249830920 cites W1997356903 @default.
• W2249830920 cites W2059707574 @default.
• W2249830920 cites W2061040802 @default.
• W2249830920 cites W2084429985 @default.
• W2249830920 cites W2092078956 @default.
• W2249830920 cites W2093188374 @default.
• W2249830920 cites W2112881842 @default.
• W2249830920 cites W2133692342 @default.
• W2249830920 cites W2242767435 @default.
• W2249830920 cites W2285459543 @default.
• W2249830920 cites W2616838800 @default.
• W2249830920 doi "https://doi.org/10.1093/bja/aev394" @default.
• W2249830920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26582864" @default.
• W2249830920 hasPublicationYear "2015" @default.
• W2249830920 type Work @default.
• W2249830920 sameAs 2249830920 @default.
• W2249830920 citedByCount "2" @default.
• W2249830920 countsByYear W22498309202020 @default.
• W2249830920 countsByYear W22498309202023 @default.
• W2249830920 crossrefType "journal-article" @default.
• W2249830920 hasAuthorship W2249830920A5013736747 @default.
• W2249830920 hasAuthorship W2249830920A5032578992 @default.
• W2249830920 hasAuthorship W2249830920A5045045289 @default.
• W2249830920 hasAuthorship W2249830920A5080363463 @default.
• W2249830920 hasBestOaLocation W22498309201 @default.
• W2249830920 hasConcept C115725540 @default.
• W2249830920 hasConcept C126322002 @default.
• W2249830920 hasConcept C164705383 @default.
• W2249830920 hasConcept C194828623 @default.
• W2249830920 hasConcept C2908647359 @default.
• W2249830920 hasConcept C36036425 @default.
• W2249830920 hasConcept C42219234 @default.
• W2249830920 hasConcept C500558357 @default.
• W2249830920 hasConcept C71924100 @default.
• W2249830920 hasConcept C99454951 @default.
• W2249830920 hasConceptScore W2249830920C115725540 @default.
• W2249830920 hasConceptScore W2249830920C126322002 @default.
• W2249830920 hasConceptScore W2249830920C164705383 @default.
• W2249830920 hasConceptScore W2249830920C194828623 @default.
• W2249830920 hasConceptScore W2249830920C2908647359 @default.
• W2249830920 hasConceptScore W2249830920C36036425 @default.
• W2249830920 hasConceptScore W2249830920C42219234 @default.
• W2249830920 hasConceptScore W2249830920C500558357 @default.
• W2249830920 hasConceptScore W2249830920C71924100 @default.
• W2249830920 hasConceptScore W2249830920C99454951 @default.
• W2249830920 hasIssue "6" @default.
• W2249830920 hasLocation W22498309201 @default.
• W2249830920 hasLocation W22498309202 @default.
• W2249830920 hasOpenAccess W2249830920 @default.
• W2249830920 hasPrimaryLocation W22498309201 @default.
• W2249830920 hasRelatedWork W2016503684 @default.
• W2249830920 hasRelatedWork W2039266278 @default.
• W2249830920 hasRelatedWork W2069297713 @default.
• W2249830920 hasRelatedWork W2090686520 @default.
• W2249830920 hasRelatedWork W2113152329 @default.
• W2249830920 hasRelatedWork W2139241385 @default.
• W2249830920 hasRelatedWork W2170496161 @default.
• W2249830920 hasRelatedWork W4303980348 @default.
• W2249830920 hasRelatedWork W94010978 @default.
• W2249830920 hasRelatedWork W2746023026 @default.
• W2249830920 hasVolume "115" @default.
• W2249830920 isParatext "false" @default.
• W2249830920 isRetracted "false" @default.
• W2249830920 magId "2249830920" @default.
• W2249830920 workType "article" @default.