FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2250262772> ?p ?o ?g. }

• W2250262772 abstract "A series of 3-hydroxypyridin-4-one derivatives (HPOs) were synthesized and their partition coefficient values (K(part)) were determined. The cytotoxic effects of these iron chelators against Hela cancer cells were also evaluated. The IC(50) of HPOs was determined using MTT assay. Among these ligands, compound 4e (K(part)=5.02) with an IC(50) of 30 μM and 4f (K(part)=0.1) with an IC(50) of 700 μM showed the lowest and highest IC(50)s, respectively. In conclusion, the introduction of a more hydrophobic functional group (such as butyl in compound 4e) on the nitrogen of pyridinone ring resulted in higher cytotoxic activity of ligands." @default.
• W2250262772 created "2016-06-24" @default.
• W2250262772 creator A5004478122 @default.
• W2250262772 creator A5017994014 @default.
• W2250262772 creator A5067255677 @default.
• W2250262772 date "2011-07-01" @default.
• W2250262772 modified "2023-09-23" @default.
• W2250262772 title "Synthesis and biological evaluation of bidentate 3-hydroxypyridin-4-ones iron chelating agents." @default.
• W2250262772 cites W1487246151 @default.
• W2250262772 cites W1513737902 @default.
• W2250262772 cites W1564880933 @default.
• W2250262772 cites W1986898208 @default.
• W2250262772 cites W1996308138 @default.
• W2250262772 cites W1998484700 @default.
• W2250262772 cites W2006379094 @default.
• W2250262772 cites W2010094123 @default.
• W2250262772 cites W2028239350 @default.
• W2250262772 cites W2032755100 @default.
• W2250262772 cites W2038039477 @default.
• W2250262772 cites W2039403847 @default.
• W2250262772 cites W2047363862 @default.
• W2250262772 cites W2049416142 @default.
• W2250262772 cites W2057932988 @default.
• W2250262772 cites W2068739696 @default.
• W2250262772 cites W2072694788 @default.
• W2250262772 cites W2080537591 @default.
• W2250262772 cites W2096825118 @default.
• W2250262772 cites W2134355296 @default.
• W2250262772 cites W2146033714 @default.
• W2250262772 cites W2237061006 @default.
• W2250262772 cites W2411088972 @default.
• W2250262772 cites W2418753837 @default.
• W2250262772 cites W2509201424 @default.
• W2250262772 cites W426804056 @default.
• W2250262772 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3249774" @default.
• W2250262772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22224095" @default.
• W2250262772 hasPublicationYear "2011" @default.
• W2250262772 type Work @default.
• W2250262772 sameAs 2250262772 @default.
• W2250262772 citedByCount "6" @default.
• W2250262772 countsByYear W22502627722013 @default.
• W2250262772 countsByYear W22502627722015 @default.
• W2250262772 countsByYear W22502627722016 @default.
• W2250262772 countsByYear W22502627722017 @default.
• W2250262772 crossrefType "journal-article" @default.
• W2250262772 hasAuthorship W2250262772A5004478122 @default.
• W2250262772 hasAuthorship W2250262772A5017994014 @default.
• W2250262772 hasAuthorship W2250262772A5067255677 @default.
• W2250262772 hasConcept C154317977 @default.
• W2250262772 hasConcept C155647269 @default.
• W2250262772 hasConcept C178516000 @default.
• W2250262772 hasConcept C178790620 @default.
• W2250262772 hasConcept C185592680 @default.
• W2250262772 hasConcept C192552737 @default.
• W2250262772 hasConcept C197404232 @default.
• W2250262772 hasConcept C202751555 @default.
• W2250262772 hasConcept C21951064 @default.
• W2250262772 hasConcept C2777366897 @default.
• W2250262772 hasConcept C2780378348 @default.
• W2250262772 hasConcept C2780783641 @default.
• W2250262772 hasConcept C544153396 @default.
• W2250262772 hasConcept C55493867 @default.
• W2250262772 hasConcept C71240020 @default.
• W2250262772 hasConceptScore W2250262772C154317977 @default.
• W2250262772 hasConceptScore W2250262772C155647269 @default.
• W2250262772 hasConceptScore W2250262772C178516000 @default.
• W2250262772 hasConceptScore W2250262772C178790620 @default.
• W2250262772 hasConceptScore W2250262772C185592680 @default.
• W2250262772 hasConceptScore W2250262772C192552737 @default.
• W2250262772 hasConceptScore W2250262772C197404232 @default.
• W2250262772 hasConceptScore W2250262772C202751555 @default.
• W2250262772 hasConceptScore W2250262772C21951064 @default.
• W2250262772 hasConceptScore W2250262772C2777366897 @default.
• W2250262772 hasConceptScore W2250262772C2780378348 @default.
• W2250262772 hasConceptScore W2250262772C2780783641 @default.
• W2250262772 hasConceptScore W2250262772C544153396 @default.
• W2250262772 hasConceptScore W2250262772C55493867 @default.
• W2250262772 hasConceptScore W2250262772C71240020 @default.
• W2250262772 hasLocation W22502627721 @default.
• W2250262772 hasOpenAccess W2250262772 @default.
• W2250262772 hasPrimaryLocation W22502627721 @default.
• W2250262772 hasRelatedWork W2006401157 @default.
• W2250262772 hasRelatedWork W2007444331 @default.
• W2250262772 hasRelatedWork W2107258344 @default.
• W2250262772 hasRelatedWork W2200938472 @default.
• W2250262772 hasRelatedWork W2226738839 @default.
• W2250262772 hasRelatedWork W2605358985 @default.
• W2250262772 hasRelatedWork W2750899296 @default.
• W2250262772 hasRelatedWork W2750955617 @default.
• W2250262772 hasRelatedWork W2775337937 @default.
• W2250262772 hasRelatedWork W2895911368 @default.
• W2250262772 hasRelatedWork W2926244526 @default.
• W2250262772 hasRelatedWork W2937161653 @default.
• W2250262772 hasRelatedWork W2968370001 @default.
• W2250262772 hasRelatedWork W2969045292 @default.
• W2250262772 hasRelatedWork W3012461838 @default.
• W2250262772 hasRelatedWork W3034589130 @default.
• W2250262772 hasRelatedWork W3038121491 @default.
• W2250262772 hasRelatedWork W3049728561 @default.
• W2250262772 hasRelatedWork W3171945181 @default.

• next