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• W2251962177 abstract "*Dom zdravlja, Svilajnac, Srbija; Medicinski fakultet Kragujevac, † Katedra za farmakologiju i toksikologiju, Kragujevac, Srbija; ‡ Agencija za lekove i medicinska sredstva, Beograd, Srbija; § Republicki zavod za zdravstveno osiguranje, Beograd, Srbija Abstract Background/Aim. High morbidity and mortality rates, chronic course of disease and numerous clinical complica- tions, make diabetes mellitus (DM) type 2 bear significant fi- nancial burden for healthcare system of Serbia. The aim of this study was to compare true disease-related expenses measured in the random sample of patients originating from the Central Serbia in 2007 and national estimate of total ex- penses based on available evidence on antidiabetic drugs and insulins acquisition costs in the same fiscal year. Methods. The study design was prevalence-based, bottom-up cost of illness analysis. It was implemented on a randomized sample of 99 adults with confirmed diagnosis of DM type 2. During 2007 all direct (drug acquisition, medical services, medical de- vices usage) and indirect costs associated with their primary disease (premature death, impaired working ability, early re- tirement, absentism), were taken into account. Other ap- proach was to calculate average national rate of antidiabetic drugs and insulin utilization and sales at the domestic market during the mentioned period of time. Taking into considera- tion available estimate from the Institute of Public Health of Serbia of 475 000 people with this disease at the national level, we were able to compare these data. Assuming that our sample was enough representative and that the structure of costs was approximately similar at the local and national level, we were able to calculate an estimate of total cost of the dis- ease. All costs were expressed in Serbian official currency, di-" @default.
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• W2251962177 date "2007-01-01" @default.
• W2251962177 modified "2023-09-27" @default.
• W2251962177 title "Procena troškova lečenja diabetes mellitus-a tip 2 u Republici Srbiji Assessment of diabetes mellitus type 2 treatment costs in the Republic of Serbia" @default.
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