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- W2252037885 abstract "Abstract Aim To assess left ventricular (LV) function in HIV patients by two-dimensional (2D) echocardiography to determine the pattern of myocardial dysfunction, and any correlation between cardiac dysfunction and severity of HIV infection. Background Human immunodeficiency virus (HIV) infection may cause various cardiac dysfunctions in humans even in the asymptomatic state and its timely detection may have prognostic value. Materials and methods One hundred treatment naive, asymptomatic HIV cases were subjected to trans-thoracic echocardiographic (2D, M-mode, pulse-wave, continuous-wave and colour Doppler) assessment by a single blinded cardiologist. Results Twenty-nine (29%) of 100 patients (mean age: 36.8 years; male: 54%) had echocardiographic abnormalities. Grade 1 diastolic dysfunction was present in 20, reduced fractional shortening in 12, reduced ejection fraction ( Cases having diastolic dysfunction had significantly different CD4 counts, haemoglobin level and erythrocyte sedimentation rate (ESR) values than the cases without cardiac dysfunction. CD4 counts were significantly negatively correlated with deceleration time (r = −0.2622, P Conclusions Twenty-nine (29%) HIV cases in relatively advanced clinical stage had cardiac dysfunction on echocardiography without overt cardiac manifestations. The CD4 cell counts significantly correlated with the presence of diastolic dysfunction." @default.
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- W2252037885 date "2016-01-01" @default.
- W2252037885 modified "2023-10-12" @default.
- W2252037885 title "Echocardiographic assessment of left ventricular function in asymptomatic HIV patients: A single arm blinded study from north India" @default.
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- W2252037885 doi "https://doi.org/10.1016/j.hivar.2015.08.002" @default.
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