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- W2252850180 abstract "Objectives In this study, the possibility of using existing test data provided in Korea and elsewhere for the registration of chemical substances was examined. Data on 510 chemical substances that are among the first subject to registration under the âAct on the Registration and Evaluation, etc. of Chemical Substances (K-REACH)â were analyzed. Methods The possibility of using existing data from 16 reference databases was examined for 510 chemical substances notified in July 2015 as being subject to registration. Results Test data with the reliability required for the registration of chemical substances under the K-REACH constituted 48.4% of the required physicochemical characteristics, 6.5% of the required health hazards, and 9.4% of the required environmental hazards. Conclusions Some existing test data were not within the scope of this research, including data used for registration in the European Union (EU). Thus, considering that 350 of these 510 species are registered in EU Registration, Evaluation, Authorisation & Restriction of Chemicals, more test data may exist that can be utilized in addition to the data identified in this study. Furthermore, the K-REACH states that non-testing data (test results predicted through Read Across, Quantitative Structure- Activity Relationships) and the weight of evidence (test results predicted based on test data with low reliability) can also be utilized for registration data. Therefore, if methods for using such data were actively reviewed, it would be possible to reduce the cost of securing test data required for the registration of chemical substances. Keywords: Act on the Registration & Evaluation, etc. of Chemical Substances, Environmental hazards, Human hazards, Phase-in substance, Physical and chemical properties" @default.
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- W2252850180 date "2015-12-23" @default.
- W2252850180 modified "2023-10-13" @default.
- W2252850180 title "Existing test data for the Act on Registration & Evaluation, etc. of Chemical Substances" @default.
- W2252850180 doi "https://doi.org/10.5620/eht.e2015017" @default.
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