FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2253313182> ?p ?o ?g. }

• W2253313182 endingPage "59" @default.
• W2253313182 startingPage "25" @default.
• W2253313182 abstract "Phosphatidylinositol 4,5-bisphosphate (PIP(2)) is a membrane bound lipid molecule with capabilities to affect a wide array of signaling pathways to regulate very different cellular processes. PIP(2) is used as a precursor to generate the second messengers PIP(3), DAG and IP(3), indispensable molecules for signaling events generated by membrane receptors. However, PIP(2) can also directly regulate a vast array of proteins and is emerging as a crucial messenger with the potential to distinctly modulate biological processes critical for both normal and pathogenic cell physiology. PIP(2) directly associates with effector proteins via unique phosphoinositide binding domains, altering their localization and/or enzymatic activity. The spatial and temporal generation of PIP(2) synthesized by the phosphatidylinositol phosphate kinases (PIPKs) tightly regulates the activation of receptor signaling pathways, endocytosis and vesicle trafficking, cell polarity, focal adhesion dynamics, actin assembly and 3' mRNA processing. Here we discuss our current understanding of PIPKs in the regulation of cellular processes from the plasma membrane to the nucleus." @default.
• W2253313182 created "2016-06-24" @default.
• W2253313182 creator A5017586422 @default.
• W2253313182 creator A5039874490 @default.
• W2253313182 creator A5046540673 @default.
• W2253313182 creator A5059763651 @default.
• W2253313182 creator A5083589251 @default.
• W2253313182 date "2012-01-01" @default.
• W2253313182 modified "2023-09-23" @default.
• W2253313182 title "PIP Kinases from the Cell Membrane to the Nucleus" @default.
• W2253313182 cites W1165872130 @default.
• W2253313182 cites W1486424890 @default.
• W2253313182 cites W1499576097 @default.
• W2253313182 cites W1500612905 @default.
• W2253313182 cites W1508167890 @default.
• W2253313182 cites W1515371688 @default.
• W2253313182 cites W1526005929 @default.
• W2253313182 cites W1536338076 @default.
• W2253313182 cites W1538989554 @default.
• W2253313182 cites W1539949968 @default.
• W2253313182 cites W1579776952 @default.
• W2253313182 cites W1589002191 @default.
• W2253313182 cites W1599789093 @default.
• W2253313182 cites W1607412327 @default.
• W2253313182 cites W1626321408 @default.
• W2253313182 cites W1629392288 @default.
• W2253313182 cites W1793858878 @default.
• W2253313182 cites W1817590197 @default.
• W2253313182 cites W1911659752 @default.
• W2253313182 cites W1965471942 @default.
• W2253313182 cites W1965476757 @default.
• W2253313182 cites W1967507934 @default.
• W2253313182 cites W1968815565 @default.
• W2253313182 cites W1971225568 @default.
• W2253313182 cites W1973643499 @default.
• W2253313182 cites W1973989092 @default.
• W2253313182 cites W1974646226 @default.
• W2253313182 cites W1976469969 @default.
• W2253313182 cites W1977121619 @default.
• W2253313182 cites W1981228379 @default.
• W2253313182 cites W1981444367 @default.
• W2253313182 cites W1981672085 @default.
• W2253313182 cites W1983063355 @default.
• W2253313182 cites W1983992348 @default.
• W2253313182 cites W1985744441 @default.
• W2253313182 cites W1985919575 @default.
• W2253313182 cites W1989367396 @default.
• W2253313182 cites W1991981480 @default.
• W2253313182 cites W1993054972 @default.
• W2253313182 cites W1993244165 @default.
• W2253313182 cites W1993828912 @default.
• W2253313182 cites W1994109113 @default.
• W2253313182 cites W1996745379 @default.
• W2253313182 cites W1997204703 @default.
• W2253313182 cites W1997227155 @default.
• W2253313182 cites W1997349759 @default.
• W2253313182 cites W1998712463 @default.
• W2253313182 cites W1999501381 @default.
• W2253313182 cites W2000221061 @default.
• W2253313182 cites W2000917393 @default.
• W2253313182 cites W2004187559 @default.
• W2253313182 cites W2004869188 @default.
• W2253313182 cites W2005664674 @default.
• W2253313182 cites W2007012814 @default.
• W2253313182 cites W2007898433 @default.
• W2253313182 cites W2008245136 @default.
• W2253313182 cites W2008680889 @default.
• W2253313182 cites W2009415695 @default.
• W2253313182 cites W2009976155 @default.
• W2253313182 cites W2010307209 @default.
• W2253313182 cites W2012678565 @default.
• W2253313182 cites W2013558343 @default.
• W2253313182 cites W2014626116 @default.
• W2253313182 cites W2015183680 @default.
• W2253313182 cites W2015778449 @default.
• W2253313182 cites W2016077331 @default.
• W2253313182 cites W2017499074 @default.
• W2253313182 cites W2019145560 @default.
• W2253313182 cites W2019590129 @default.
• W2253313182 cites W2020257412 @default.
• W2253313182 cites W2020472510 @default.
• W2253313182 cites W2021682292 @default.
• W2253313182 cites W2022447069 @default.
• W2253313182 cites W2022538712 @default.
• W2253313182 cites W2022867145 @default.
• W2253313182 cites W2023119588 @default.
• W2253313182 cites W2023712216 @default.
• W2253313182 cites W2024797145 @default.
• W2253313182 cites W2025804691 @default.
• W2253313182 cites W2026463319 @default.
• W2253313182 cites W2027231986 @default.
• W2253313182 cites W2027298203 @default.
• W2253313182 cites W2027557494 @default.
• W2253313182 cites W2028940392 @default.
• W2253313182 cites W2030107341 @default.
• W2253313182 cites W2031735540 @default.
• W2253313182 cites W2031874417 @default.
• W2253313182 cites W2032372404 @default.

• next