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- W2254486044 abstract "Objective: To investigate the association between environmental exposure (living environment and production environment) to crocidolite and the cancer mortality risk. Methods: A cohort including 1 249 healthy residents recruited from crocidolite-contaminated (1.642-3.935), respectively; compared with population not engaged in material processing, the HRs (95% CIs) for cancer mortality in populations using crushing machine in material processing and hand-crushing in material processing were 1.811 (1.211-2.709) and 1.785 (1.072-2.793), respectively; the HRs (95% CIs) for cancer mortality in populations whitewashing the wall for 4 times or more, building the masonry stove and starching clothing with slurry were 1.736 (1.000-3.012), 2.229 (0.97-5.122) and 3.307 (1.522-7.184), respectively. Conclusion: Exposure to crocidolite in living environment and production environment may increase the risk for cancer mortality.area in Dayao County, Yunnan Province in 1984 was retrospectively analyzed. The COX regression model was used to estimate hazard ratio (HR) and 95% confidence interval (CI) for cancer mortality according to time of exposure to crocidolite and the crocidolite exposure in the production and living environments of blast-furnace manufacturing, material processing, whitewashing the wall, masonry stove building, and starching clothing with slurry. Results: A total of one hundred and twenty-one deaths were identified by April 30, 2011. After adjusting for the confounding factors including age, gender, marriage, education, smoking and alcohol consumption, it was found that as compared with population exposed to crocidolite in five years or less, HRs (95% CIs) for cancer mortality in populations exposed to crocidolite in 6-10, 11-15 and more than 15 years were 2.898 (1.496-5.616), 4.159 (2.169-7.975), and 4.233 (1.182-9.886), respectively, and a dose-response relationship (Ptrend＜0.05) was observed; compared with population not engaged in production of blast-furnace, the HRs (95% CIs) for cancer mortality in populations engaged in sporadic production and mass production of blast-furnace were 2.533 (1.549-4.142) and 2.541 DOI:10.3781/j.issn.1000-7431.2012.07.006" @default.
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- W2254486044 date "2012-07-25" @default.
- W2254486044 modified "2023-09-27" @default.
- W2254486044 title "Malignant tumor-related mortality in crocidolite-contaminated area of Dayao County in Yunnan Province in China: A 27-year retrospective cohort study" @default.
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