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- W2254571759 abstract "Objective: To determine the prevalence and susceptibility pattern of MRSA isolated at a single tertiary care hospital atRawalpindi and to compare MRSA susceptibility pattern with MSSA (Methicillin sensitive staphylococcus aureus).Study Design: Descriptive cross sectional data based study.Place and Duration of Study: The study was conducted at department of microbiology, Pakistan Railways HospitalRawalpindi, from January 2012 to March 2014.Materials and Methods: Culture reports data were retrospectively collected from microbiology laboratory. The antibioticsusceptibility patterns of all staphylococcal strains were determined by modified Kirby Bauer antibiotic sensitivity method.The data was analyzed on the basis of antimicrobial susceptibility pattern, location of the patient (OPD, ward patients) andspecimen type (wound swab, pus, HVS & effusions).Results: A total of 167 isolates were used in the study. Among these isolates 55 (33%) were MRSA and 112 (67%) wereMSSA. The majority of S.aureus isolates were obtained from patients with skin and soft tissue infections. All (100%) strainsof MRSA isolated during study period were found to be sensitive to Vancomycin, and linezolid and 95% to Teicoplanin, aswell as they showed higher susceptibility against chloramphenicol (88%),Fusidic acid (70%) and Rifampin (48%)whileMSSA showed higher susceptibility to Gentamicin (92%),Erythromycin (86%) and Ciprofloxacin (71%) as compared toMRSA.Conclusion: This study showed a high prevalence of MRSA in this tertiary care hospital of Rawalpindi. Present studyconclusively shows that Vancomycin, Linezolid and Teicoplanin remain the first choice of treatment for MRSA infections.Still alternative antibiotics like chloramphenicol, Fusidic acid, and Rifampin are available to maintain and reserve theefficacy of Vancomycin, Teicoplanin and Linezolid in treating life threatening illnesses." @default.
- W2254571759 created "2016-06-24" @default.
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- W2254571759 date "2015-01-01" @default.
- W2254571759 modified "2023-09-23" @default.
- W2254571759 title "Prevalence and Susceptibility Pattern of Methicillin Resistant Staphylococcus aureus (MRSA)" @default.
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