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- W2255302213 abstract "The inherent role of [Ca^+jj on the shear-induced polymerization of cytoskeleton was proposed by the flow chamber experiments and the mathematical modeling of cytosolic calcium oscillations to access the correlation of signal transduction and the mechanotransduction of endothelial cells. From the results of flow chamber experiments of endothelial cells adhered on the fibronectin, the opening characteristic of membrane-bound calcium channel was assumed to biphasic function to the exposure time of shear stress. With this modification, the model for IPs-induced calcium oscillation shows a good agreement with the waveforms of shear-induced cytosolic calcium oscillations measured with digital fluorescence imaging of fura-2-loaded endothelial cells. This result shows the polymerization of cytoskeleton may closely correlate with the periodic formation of IPg and cytosolic calcium oscillations by a shear stress." @default.
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- W2255302213 date "1970-01-01" @default.
- W2255302213 modified "2023-09-22" @default.
- W2255302213 title "Mathematical Model For Shear-induced CytosolicCalcium Oscillations: The Role Of (ca2+)i InCytoskeleton Organisations" @default.
- W2255302213 doi "https://doi.org/10.2495/bio950081" @default.
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