Matches in SemOpenAlex for { <https://semopenalex.org/work/W2255305418> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2255305418 endingPage "87" @default.
- W2255305418 startingPage "1379" @default.
- W2255305418 abstract "The antinociceptive effect of purine nucleotides administered systematically (sc) was determined using the formalin and writhing tests in adult male albino mice. The mechanisms underlying nucleotide-induced antinociception were investigated by preinjecting the animals (sc) with specific antagonists for opioid (naloxone, 1 mg/kg), purinergic P1 (caffeine, 5, 10, of 30 mg/kg); theophylline, 10 mg/kg) or purinergic P2 receptors (suramin, 100 mg/kg; Coomassie blue, 30-300 mg/kg; quinidine, 10 mg/kg). Adenosine, adenosine monophosphate (AMP), diphosphate (ADP) and triphosphate (ATP) caused a reduction in the number of writhes and in the time of licking the formalin-injected paw. Naloxone had no effect on adenosine- or adenine nucleotide-induced antinociception. Caffeine (30 mg/kg) and theophylline (10 mg/kg) reversed the antinociceptive action of adenosine and adenine nucleotide derivatives in both tests. P2 antagonists did not reverse adenine nucleotide-induced antinociception. These results suggest that antinociceptive effect of adenine nucleotides is mediated by adenosine." @default.
- W2255305418 created "2016-06-24" @default.
- W2255305418 creator A5002946751 @default.
- W2255305418 creator A5005494740 @default.
- W2255305418 creator A5008720970 @default.
- W2255305418 creator A5023872830 @default.
- W2255305418 creator A5046481836 @default.
- W2255305418 creator A5049939706 @default.
- W2255305418 creator A5062872247 @default.
- W2255305418 creator A5088744338 @default.
- W2255305418 date "1996-10-01" @default.
- W2255305418 modified "2023-09-23" @default.
- W2255305418 title "Antinociceptive effect of purine nucleotides." @default.
- W2255305418 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9181113" @default.
- W2255305418 hasPublicationYear "1996" @default.
- W2255305418 type Work @default.
- W2255305418 sameAs 2255305418 @default.
- W2255305418 citedByCount "0" @default.
- W2255305418 crossrefType "journal-article" @default.
- W2255305418 hasAuthorship W2255305418A5002946751 @default.
- W2255305418 hasAuthorship W2255305418A5005494740 @default.
- W2255305418 hasAuthorship W2255305418A5008720970 @default.
- W2255305418 hasAuthorship W2255305418A5023872830 @default.
- W2255305418 hasAuthorship W2255305418A5046481836 @default.
- W2255305418 hasAuthorship W2255305418A5049939706 @default.
- W2255305418 hasAuthorship W2255305418A5062872247 @default.
- W2255305418 hasAuthorship W2255305418A5088744338 @default.
- W2255305418 hasConcept C104317684 @default.
- W2255305418 hasConcept C115955781 @default.
- W2255305418 hasConcept C134018914 @default.
- W2255305418 hasConcept C15490471 @default.
- W2255305418 hasConcept C170493617 @default.
- W2255305418 hasConcept C181199279 @default.
- W2255305418 hasConcept C185592680 @default.
- W2255305418 hasConcept C2776182878 @default.
- W2255305418 hasConcept C2776476023 @default.
- W2255305418 hasConcept C2776991684 @default.
- W2255305418 hasConcept C2778095195 @default.
- W2255305418 hasConcept C2778500429 @default.
- W2255305418 hasConcept C2778750930 @default.
- W2255305418 hasConcept C2779876172 @default.
- W2255305418 hasConcept C2781063702 @default.
- W2255305418 hasConcept C2994266630 @default.
- W2255305418 hasConcept C512185932 @default.
- W2255305418 hasConcept C55493867 @default.
- W2255305418 hasConcept C57306754 @default.
- W2255305418 hasConcept C67018056 @default.
- W2255305418 hasConcept C86803240 @default.
- W2255305418 hasConcept C98274493 @default.
- W2255305418 hasConceptScore W2255305418C104317684 @default.
- W2255305418 hasConceptScore W2255305418C115955781 @default.
- W2255305418 hasConceptScore W2255305418C134018914 @default.
- W2255305418 hasConceptScore W2255305418C15490471 @default.
- W2255305418 hasConceptScore W2255305418C170493617 @default.
- W2255305418 hasConceptScore W2255305418C181199279 @default.
- W2255305418 hasConceptScore W2255305418C185592680 @default.
- W2255305418 hasConceptScore W2255305418C2776182878 @default.
- W2255305418 hasConceptScore W2255305418C2776476023 @default.
- W2255305418 hasConceptScore W2255305418C2776991684 @default.
- W2255305418 hasConceptScore W2255305418C2778095195 @default.
- W2255305418 hasConceptScore W2255305418C2778500429 @default.
- W2255305418 hasConceptScore W2255305418C2778750930 @default.
- W2255305418 hasConceptScore W2255305418C2779876172 @default.
- W2255305418 hasConceptScore W2255305418C2781063702 @default.
- W2255305418 hasConceptScore W2255305418C2994266630 @default.
- W2255305418 hasConceptScore W2255305418C512185932 @default.
- W2255305418 hasConceptScore W2255305418C55493867 @default.
- W2255305418 hasConceptScore W2255305418C57306754 @default.
- W2255305418 hasConceptScore W2255305418C67018056 @default.
- W2255305418 hasConceptScore W2255305418C86803240 @default.
- W2255305418 hasConceptScore W2255305418C98274493 @default.
- W2255305418 hasIssue "10" @default.
- W2255305418 hasLocation W22553054181 @default.
- W2255305418 hasOpenAccess W2255305418 @default.
- W2255305418 hasPrimaryLocation W22553054181 @default.
- W2255305418 hasRelatedWork W1974212207 @default.
- W2255305418 hasRelatedWork W2000937353 @default.
- W2255305418 hasRelatedWork W2035171570 @default.
- W2255305418 hasRelatedWork W2044588883 @default.
- W2255305418 hasRelatedWork W2061424170 @default.
- W2255305418 hasRelatedWork W2091752732 @default.
- W2255305418 hasRelatedWork W2121922233 @default.
- W2255305418 hasRelatedWork W2142332229 @default.
- W2255305418 hasRelatedWork W2255305418 @default.
- W2255305418 hasRelatedWork W81933992 @default.
- W2255305418 hasVolume "29" @default.
- W2255305418 isParatext "false" @default.
- W2255305418 isRetracted "false" @default.
- W2255305418 magId "2255305418" @default.
- W2255305418 workType "article" @default.