Matches in SemOpenAlex for { <https://semopenalex.org/work/W2255351464> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2255351464 endingPage "815" @default.
- W2255351464 startingPage "811" @default.
- W2255351464 abstract "Objective To analyze the human IL-10-819 C/C and TNF-α-1031 C/C genes and their association with susceptibility of gastroduodenal diseases and provide new ideas and methods for clinical diagnosis and prevention of the disease.Method 51 H.pylori-positive patients with gastric ulcer,43 patients with gastric cancer and 100 healthy H.pylori positive controls were genotyped for IL-1B-31,TNF-A-308 and TNF-A-857 gene polymorphisms by the PCR-RFLP and ASP-PCR method.Statistical analysis of their polymorphism was performed.Result The frequencies of TNF-A-1031 genotypes in gastric ulcer group were significantly different from the control group(χ2=9.464,P0.001),so were the frequencies of TNF-A-1031 genotypes in gastric cancer group(χ2=9.335,P0.001).Multivariate logistic regression analysis showed that the subjects carrying TNF-A-1031 C/C genotype were at a 7-fold elevated risk for gastric ulcer,OR=7.60(95%CI: 1.38-41.77),compared to those carrying TNF-A-3-1031 T/T;the subjects carrying TNF-A-1031 C/C genotype were at a 5-fold elevated risk for gastric ulcer OR= 5.84(95%CI: 1.00-33.84),compared to those carrying TNF-A-3-1031 T/T.The subjects carrying TNF-A-1031 C/C genotype were at a 7-fold elevated risk for gastric ulcer,OR=7.94(95%CI: 1.44-43.67),compared to those carrying TNF-A-1031 T/T;The subjects carrying TNF-A-1031 T/T genotype were at a 6-fold elevated risk for gastric cancer,OR=6.95(95%CI:1.19-40.63)compared to those carrying TNF-A-1031 C/C.IL-10-819 genotype distribution was not statistically significant in the disease group and the control group.Conclusion The polymorphism of TNF-α-1031 gene has close association with susceptibility of gastric ulcer and gastric cancer." @default.
- W2255351464 created "2016-06-24" @default.
- W2255351464 creator A5017557124 @default.
- W2255351464 creator A5042118154 @default.
- W2255351464 creator A5053718537 @default.
- W2255351464 creator A5058481800 @default.
- W2255351464 creator A5070242722 @default.
- W2255351464 creator A5079207956 @default.
- W2255351464 date "2010-01-01" @default.
- W2255351464 modified "2023-09-24" @default.
- W2255351464 title "Association between IL-10-819 C/C and TNF-α-1031 C/C genes and susceptibility of gastrodnodenai diseases." @default.
- W2255351464 hasPublicationYear "2010" @default.
- W2255351464 type Work @default.
- W2255351464 sameAs 2255351464 @default.
- W2255351464 citedByCount "0" @default.
- W2255351464 crossrefType "journal-article" @default.
- W2255351464 hasAuthorship W2255351464A5017557124 @default.
- W2255351464 hasAuthorship W2255351464A5042118154 @default.
- W2255351464 hasAuthorship W2255351464A5053718537 @default.
- W2255351464 hasAuthorship W2255351464A5058481800 @default.
- W2255351464 hasAuthorship W2255351464A5070242722 @default.
- W2255351464 hasAuthorship W2255351464A5079207956 @default.
- W2255351464 hasConcept C104317684 @default.
- W2255351464 hasConcept C126322002 @default.
- W2255351464 hasConcept C135763542 @default.
- W2255351464 hasConcept C151956035 @default.
- W2255351464 hasConcept C17991360 @default.
- W2255351464 hasConcept C203014093 @default.
- W2255351464 hasConcept C54355233 @default.
- W2255351464 hasConcept C71924100 @default.
- W2255351464 hasConcept C86803240 @default.
- W2255351464 hasConcept C90924648 @default.
- W2255351464 hasConceptScore W2255351464C104317684 @default.
- W2255351464 hasConceptScore W2255351464C126322002 @default.
- W2255351464 hasConceptScore W2255351464C135763542 @default.
- W2255351464 hasConceptScore W2255351464C151956035 @default.
- W2255351464 hasConceptScore W2255351464C17991360 @default.
- W2255351464 hasConceptScore W2255351464C203014093 @default.
- W2255351464 hasConceptScore W2255351464C54355233 @default.
- W2255351464 hasConceptScore W2255351464C71924100 @default.
- W2255351464 hasConceptScore W2255351464C86803240 @default.
- W2255351464 hasConceptScore W2255351464C90924648 @default.
- W2255351464 hasIssue "9" @default.
- W2255351464 hasLocation W22553514641 @default.
- W2255351464 hasOpenAccess W2255351464 @default.
- W2255351464 hasPrimaryLocation W22553514641 @default.
- W2255351464 hasRelatedWork W1977329209 @default.
- W2255351464 hasRelatedWork W2008571337 @default.
- W2255351464 hasRelatedWork W2105755890 @default.
- W2255351464 hasRelatedWork W2111116847 @default.
- W2255351464 hasRelatedWork W2116841148 @default.
- W2255351464 hasRelatedWork W2160843069 @default.
- W2255351464 hasRelatedWork W2352563612 @default.
- W2255351464 hasRelatedWork W2375168852 @default.
- W2255351464 hasRelatedWork W2384605647 @default.
- W2255351464 hasRelatedWork W2385147033 @default.
- W2255351464 hasRelatedWork W2387663684 @default.
- W2255351464 hasRelatedWork W2464998802 @default.
- W2255351464 hasRelatedWork W2507791602 @default.
- W2255351464 hasRelatedWork W2567011622 @default.
- W2255351464 hasRelatedWork W2607187075 @default.
- W2255351464 hasRelatedWork W3028775989 @default.
- W2255351464 hasRelatedWork W342583221 @default.
- W2255351464 hasRelatedWork W996470125 @default.
- W2255351464 hasRelatedWork W2167045412 @default.
- W2255351464 hasRelatedWork W274250415 @default.
- W2255351464 hasVolume "22" @default.
- W2255351464 isParatext "false" @default.
- W2255351464 isRetracted "false" @default.
- W2255351464 magId "2255351464" @default.
- W2255351464 workType "article" @default.