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- W2255502062 abstract "Osteoartheritis is a degenerative joint disease characterized by gradualdegeneration of the joint cartilage, osteophyte formation, fibrillation and articular cartilage cracks.Platelet rich plasma (PRP) contains growth factors and promotes regeneration of bones. Therefore thepurpose of this study was to investigate the effects of PRP on cartilage repair in the osteoarthritismodel in rabbits.Materials &Methods: In this study, 25 white New Zealand rabbits of both sexes were used. Theanterior cruciate ligament of the right knee joint was resisted under general anesthesia. Eight weeksfollowing the operation, they were divided into five groups. The first group served as the control groupthat received no treatment. The rest of rabbits received autogenic PRP in their joints. The rabbits wereeuthanized and the joints were sampled for histopathologic study at 8 and 12 weeks post PRPinjection.Results: The results proved that the autogenic PRP is rich of growth factors and repairs thedegenerated joints histology significantly compared to the control group and is useful in the treatmentof osteoarthritis.Conclusion: PRP can be used to treat the joints affected by oateoarhteritis" @default.
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- W2255502062 date "2015-05-15" @default.
- W2255502062 modified "2023-09-27" @default.
- W2255502062 title "THE EFFECT OF PRP IN REPAIR OF FEMORAL ARTICULAR CARTILAGE NOTCHES ON EXPERIMENTALLY INDUCED OSTEOARTHRITIS RABBIT" @default.
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