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- W2255602011 abstract "The use of isoniazid (INH) in persons exposed to active cases of tuberculosis has been challenged, Reports of toxic reactions to isoniazid warrant a review of the drug's potential benefits and hazards. This prompted a retrospective survey of cases admitted to a large county hospital to determine admission incidence before and since initiation of a program of case-finding and INH chemoprophylaxis for children in 1953. During the 24-year period surveyed (1950-1973), the population of the county increased twofold while the yearly admission rate for tuberculous meningitis in children fell from a high of eight cases to a low of two. This dramatic drop in cases admitted, coupled with an absence of any toxic reactions to the drug, provides support for continuation of the program of case-finding and isoniazid chemoprophylaxis." @default.
- W2255602011 created "2016-06-24" @default.
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- W2255602011 date "1976-08-01" @default.
- W2255602011 modified "2023-09-26" @default.
- W2255602011 title "Tuberculous Meningitis in Children Before and Since Isoniazid" @default.
- W2255602011 doi "https://doi.org/10.1097/00007611-197608000-00033" @default.
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