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- W2256296776 abstract "Animal derived natural products contributed a major part in traditional medicine to prevent inflammation related diseases. The proposed work was aimed to study on the extrapallial fluid of the freshwater mollusca, Bellamya bengalensis (L), family Viviparidae in experimental regimes. The extrapallial fluid of Bellamya bengalensis was inspirited out, partially purified with centrifugation (3500 rpm for 15 min at 4°C) and standardized using protein calibration (BBE). The bioactivities of BBE were examined for erythrocytes membrane stabilizing, protein denaturation inhibiting and proteinase inhibiting actions in test tubes. Further, carrageenan induced acute and Freund’s adjuvant induced sub-acute paw inflammations were conducted in rats. Finally, central analgesic activities were also done using Eddy’s hot plate and tail immersion tests. BBE contained ~0.1% proteins in slightly acidic medium (pH 6.6) and exhibited significant proteinase inhibitory actions and membrane stabilizing properties. BBE showed dose dependent inhibition in rat paw inflammation measured plethysmographically and also histopathologically. It also showed significant analgesic properties in mice. The results indicated the analgesic and anti-inflammatory actions of extrapallial fluid of Bellamya bengalensis." @default.
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- W2256296776 date "2015-07-28" @default.
- W2256296776 modified "2023-09-27" @default.
- W2256296776 title "Anti-Inflammatory Activities of Indian Fresh Water Edible Mollusca" @default.
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- W2256296776 doi "https://doi.org/10.6084/m9.figshare.1495328.v1" @default.
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