Matches in SemOpenAlex for { <https://semopenalex.org/work/W2256992908> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2256992908 abstract "The treatment for most psychotic patients was largely ineffectual and care primarily custodial until the discovery of the antipsychotic properties of chlorpromazine in 1953. Ten years later Carlsson and Lindqvist (1963) discovered that antipsychotic drugs (neuroleptics) exert a specific action on central catecholamine systems, and hypothesized that they produced their effects by blocking catecholamine receptors in catecholamine-innervated sites. They further posited that the receptor blockade resulted in an increase in catecholamine neuronal activity which was mediated through long-loop feedback pathways from forebrain regions innervated by catecholamine neurons (Carlsson and Lindqvist 1963). This concept was a major impetus behind the last two decades of research on the mode of action of neuroleptics. During this time the dopamine (DA) system has been the primary focus of attention and DA receptor blockers have continued to be the treatment of choice for the major symptoms of psychosis (Klein et al. 1980)." @default.
- W2256992908 created "2016-06-24" @default.
- W2256992908 creator A5052613895 @default.
- W2256992908 creator A5078169211 @default.
- W2256992908 date "1987-01-01" @default.
- W2256992908 modified "2023-09-24" @default.
- W2256992908 title "Chronic Neuroleptic Effects on Dopamine Neuron Activity: A Model for Predicting Therapeutic Efficacy and Side Effects?" @default.
- W2256992908 cites W1561239748 @default.
- W2256992908 cites W1569664741 @default.
- W2256992908 cites W189363520 @default.
- W2256992908 cites W1961847285 @default.
- W2256992908 cites W1965671642 @default.
- W2256992908 cites W1973729800 @default.
- W2256992908 cites W1975520016 @default.
- W2256992908 cites W1978618811 @default.
- W2256992908 cites W1982522522 @default.
- W2256992908 cites W1992341044 @default.
- W2256992908 cites W1994993913 @default.
- W2256992908 cites W1998892676 @default.
- W2256992908 cites W2004071839 @default.
- W2256992908 cites W2014279016 @default.
- W2256992908 cites W2017887966 @default.
- W2256992908 cites W2044391863 @default.
- W2256992908 cites W2049074524 @default.
- W2256992908 cites W2050136925 @default.
- W2256992908 cites W2051047041 @default.
- W2256992908 cites W2067578791 @default.
- W2256992908 cites W2071389360 @default.
- W2256992908 cites W2073995430 @default.
- W2256992908 cites W2080781871 @default.
- W2256992908 cites W2081862427 @default.
- W2256992908 cites W2091195924 @default.
- W2256992908 cites W2125707130 @default.
- W2256992908 cites W2159996636 @default.
- W2256992908 cites W4243358005 @default.
- W2256992908 doi "https://doi.org/10.1007/978-3-642-71288-3_26" @default.
- W2256992908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2881290" @default.
- W2256992908 hasPublicationYear "1987" @default.
- W2256992908 type Work @default.
- W2256992908 sameAs 2256992908 @default.
- W2256992908 citedByCount "7" @default.
- W2256992908 countsByYear W22569929082013 @default.
- W2256992908 countsByYear W22569929082017 @default.
- W2256992908 crossrefType "book-chapter" @default.
- W2256992908 hasAuthorship W2256992908A5052613895 @default.
- W2256992908 hasAuthorship W2256992908A5078169211 @default.
- W2256992908 hasConcept C118552586 @default.
- W2256992908 hasConcept C120069818 @default.
- W2256992908 hasConcept C126322002 @default.
- W2256992908 hasConcept C15744967 @default.
- W2256992908 hasConcept C169760540 @default.
- W2256992908 hasConcept C170493617 @default.
- W2256992908 hasConcept C2775894120 @default.
- W2256992908 hasConcept C2776412080 @default.
- W2256992908 hasConcept C2778468042 @default.
- W2256992908 hasConcept C2778775820 @default.
- W2256992908 hasConcept C2779727114 @default.
- W2256992908 hasConcept C2780494398 @default.
- W2256992908 hasConcept C44208683 @default.
- W2256992908 hasConcept C513476851 @default.
- W2256992908 hasConcept C71924100 @default.
- W2256992908 hasConcept C98274493 @default.
- W2256992908 hasConceptScore W2256992908C118552586 @default.
- W2256992908 hasConceptScore W2256992908C120069818 @default.
- W2256992908 hasConceptScore W2256992908C126322002 @default.
- W2256992908 hasConceptScore W2256992908C15744967 @default.
- W2256992908 hasConceptScore W2256992908C169760540 @default.
- W2256992908 hasConceptScore W2256992908C170493617 @default.
- W2256992908 hasConceptScore W2256992908C2775894120 @default.
- W2256992908 hasConceptScore W2256992908C2776412080 @default.
- W2256992908 hasConceptScore W2256992908C2778468042 @default.
- W2256992908 hasConceptScore W2256992908C2778775820 @default.
- W2256992908 hasConceptScore W2256992908C2779727114 @default.
- W2256992908 hasConceptScore W2256992908C2780494398 @default.
- W2256992908 hasConceptScore W2256992908C44208683 @default.
- W2256992908 hasConceptScore W2256992908C513476851 @default.
- W2256992908 hasConceptScore W2256992908C71924100 @default.
- W2256992908 hasConceptScore W2256992908C98274493 @default.
- W2256992908 hasLocation W22569929081 @default.
- W2256992908 hasLocation W22569929082 @default.
- W2256992908 hasOpenAccess W2256992908 @default.
- W2256992908 hasPrimaryLocation W22569929081 @default.
- W2256992908 hasRelatedWork W1973576252 @default.
- W2256992908 hasRelatedWork W1985302532 @default.
- W2256992908 hasRelatedWork W1986778811 @default.
- W2256992908 hasRelatedWork W1989459745 @default.
- W2256992908 hasRelatedWork W1991861361 @default.
- W2256992908 hasRelatedWork W2010174773 @default.
- W2256992908 hasRelatedWork W2085688436 @default.
- W2256992908 hasRelatedWork W2086636867 @default.
- W2256992908 hasRelatedWork W2091680463 @default.
- W2256992908 hasRelatedWork W2899084033 @default.
- W2256992908 isParatext "false" @default.
- W2256992908 isRetracted "false" @default.
- W2256992908 magId "2256992908" @default.
- W2256992908 workType "book-chapter" @default.