FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2257037308> ?p ?o ?g. }

• W2257037308 endingPage "536" @default.
• W2257037308 startingPage "536" @default.
• W2257037308 abstract "We report a case treated by veno-venoarterial extracorporeal membrane oxygenation (vva-ECMO) for stress cardiomyopathy due to exacerbation of asthma.A 45-year-old woman with a history of asthma was transferred to our emergency department from a local medical center. She had developed severe dyspnea and wheezing an hour before. At the time of arrival at our hospital, she was already intubated and had been administered systemic corticosteroid. The initial blood pressure (BP) was 140/90 mm Hg, and heart rate was 130 beats per minute. Her arterial blood gas analysis (ABGA) showed PaO2 18 mm Hg, PaCO2 88 mm Hg, and SaO2 9%. She initiated on ventilator care with FiO2 1.0. Initial transthoracic echocardiography (TTE) showed that left ventricular ejection fraction (LVEF) was 45%. Her electrocardiogram (ECG) was sinus tachycardia without ST-segment abnormalities, and troponin I was 0.11 ng/mL. Computed tomography revealed diffuse tracheobronchial narrowing in both lung fields, which was compatible with acute exacerbation of chronic asthma. Despite 12 hours of ventilator care, hypoxia and hypercapnia developed (PaO2/FiO2 73 mm Hg/0.5, PaCO2 118 mm Hg). Our ECMO team was contacted and decided to apply veno-venous extracorporeal membrane oxygenation (vv-ECMO) via bilateral femoral veins: RotaFlow centrifugal pump (Maquet cardiopulmonary AG, Hirrlingen, Germany), a 20 Fr femoral venous cannula (Fem-Flex II, Edwards Lifescience, LLC, Irvine, CA, USA), a 21 Fr femoral venous cannula (DLP, Medtronic Inc., Minneapolis, MN, USA). ECMO was initiated and gas exchange improved: PaO2 172 mm Hg on ventilator FiO2 0.4, PaCO2 43 mm Hg, peripheral SaO2 99%.Thirty minutes after the start of ECMO, arterial BP dropped below 40/20 mm Hg. Despite the high dose of catecholamines, systolic BP was below 60 mm Hg. TTE showed LVEF of 15% and global wall motion abnormality of LV. ECG presented nonspecific T-wave inversion and troponin I was slightly increased (2.18 ng/mL). We postulated that she developed stress cardiomyopathy due to exacerbation of asthma, because she had no clinical history suggestive of acute coronary syndrome. We converted vv-ECMO to vva-ECMO by insertion of an arterial cannula via the left femoral artery: a 16 Fr femoral arterial cannula (Fem-Flex II, Edwards Lifescience), connected to ECMO via the Y-connector.After 15 hours of vva-ECMO support, follow-up TTE showed LVEF of 35% and mid-ventricular akinesia and apical hypokinesia (Fig. 1). We reverted to vv-ECMO on the 3rd day. On the 4th day, the ECMO was weaned off without significant complications. On the 7th day, she was extubated, and transferred to a general ward the following day. She underwent rehabilitation for 2 weeks, and was subsequently discharged from the hospital.Fig. 1On the 2nd day ECMO insertion, transthoracic echocardiography (TTE) shows mid-ventricular akinesia and apical hypokinesia.Asthma has a high prevalence world-wide, and can be fatal in some cases. Asthma with acute exacerbation often leads to respiratory failure requiring mechanical ventilation.1 vv-ECMO is helpful when a patient has persistent hypoxemia and hypercapnia despite maximal ventilator support.2 We initially provided our patient with vv-ECMO for respiratory support. After a while, her cardiac function deteriorated rapidly with low BP, low LVEF, global wall motion abnormality of LV, nonspecific T-wave inversion on ECG, and increased troponin I. We considered that she developed stress cardiomyopathy due to severe respiratory failure. Coronary angiography to exclude obstructive coronary disease was not performed, since the patient had no implicating history. She was in cardiogenic shock refractory to fluid and high dose inotropic drugs.The studies on vva-ECMO are limited. A small-cohort study showed that vva-ECMO appears to further improve survival in the acute respiratory distress syndrome.3 Because vva-ECMO provides well-oxygenated blood to the systemic and pulmonary circulation, it helps reduce the pulmonary resistance and the existence of intrapulmonary-shunts in the pulmonary circulation. It also supplies sufficient oxygen to the coronary and peripheral organs.vva-ECMO is beneficial for supporting both cardiac function and respiratory function in acute respiratory failure combined with cardiac failure, as in the current case." @default.
• W2257037308 created "2016-06-24" @default.
• W2257037308 creator A5015751637 @default.
• W2257037308 creator A5026800270 @default.
• W2257037308 creator A5031582314 @default.
• W2257037308 creator A5045317661 @default.
• W2257037308 creator A5050277676 @default.
• W2257037308 date "2016-01-01" @default.
• W2257037308 modified "2023-09-25" @default.
• W2257037308 title "Successful Application of Veno-Venoarterial Extracorporeal Membrane Oxygenation for Acute Exacerbation of Asthma Followed by Stress Cardiomyopathy" @default.
• W2257037308 cites W1513845439 @default.
• W2257037308 cites W1966136315 @default.
• W2257037308 cites W1979161727 @default.
• W2257037308 doi "https://doi.org/10.3349/ymj.2016.57.2.536" @default.
• W2257037308 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4740554" @default.
• W2257037308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26847314" @default.
• W2257037308 hasPublicationYear "2016" @default.
• W2257037308 type Work @default.
• W2257037308 sameAs 2257037308 @default.
• W2257037308 citedByCount "3" @default.
• W2257037308 countsByYear W22570373082016 @default.
• W2257037308 countsByYear W22570373082019 @default.
• W2257037308 countsByYear W22570373082022 @default.
• W2257037308 crossrefType "journal-article" @default.
• W2257037308 hasAuthorship W2257037308A5015751637 @default.
• W2257037308 hasAuthorship W2257037308A5026800270 @default.
• W2257037308 hasAuthorship W2257037308A5031582314 @default.
• W2257037308 hasAuthorship W2257037308A5045317661 @default.
• W2257037308 hasAuthorship W2257037308A5050277676 @default.
• W2257037308 hasBestOaLocation W22570373081 @default.
• W2257037308 hasConcept C126322002 @default.
• W2257037308 hasConcept C164705383 @default.
• W2257037308 hasConcept C2776042228 @default.
• W2257037308 hasConcept C2776858399 @default.
• W2257037308 hasConcept C2777014857 @default.
• W2257037308 hasConcept C2778198053 @default.
• W2257037308 hasConcept C2778797674 @default.
• W2257037308 hasConcept C2909082789 @default.
• W2257037308 hasConcept C71924100 @default.
• W2257037308 hasConceptScore W2257037308C126322002 @default.
• W2257037308 hasConceptScore W2257037308C164705383 @default.
• W2257037308 hasConceptScore W2257037308C2776042228 @default.
• W2257037308 hasConceptScore W2257037308C2776858399 @default.
• W2257037308 hasConceptScore W2257037308C2777014857 @default.
• W2257037308 hasConceptScore W2257037308C2778198053 @default.
• W2257037308 hasConceptScore W2257037308C2778797674 @default.
• W2257037308 hasConceptScore W2257037308C2909082789 @default.
• W2257037308 hasConceptScore W2257037308C71924100 @default.
• W2257037308 hasIssue "2" @default.
• W2257037308 hasLocation W22570373081 @default.
• W2257037308 hasLocation W22570373082 @default.
• W2257037308 hasLocation W22570373083 @default.
• W2257037308 hasLocation W22570373084 @default.
• W2257037308 hasOpenAccess W2257037308 @default.
• W2257037308 hasPrimaryLocation W22570373081 @default.
• W2257037308 hasRelatedWork W1957770986 @default.
• W2257037308 hasRelatedWork W1985426726 @default.
• W2257037308 hasRelatedWork W2098935330 @default.
• W2257037308 hasRelatedWork W2320829605 @default.
• W2257037308 hasRelatedWork W2564498768 @default.
• W2257037308 hasRelatedWork W2570744834 @default.
• W2257037308 hasRelatedWork W2943761215 @default.
• W2257037308 hasRelatedWork W2962939929 @default.
• W2257037308 hasRelatedWork W3157235339 @default.
• W2257037308 hasRelatedWork W4225925351 @default.
• W2257037308 hasVolume "57" @default.
• W2257037308 isParatext "false" @default.
• W2257037308 isRetracted "false" @default.
• W2257037308 magId "2257037308" @default.
• W2257037308 workType "article" @default.