FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2257277670> ?p ?o ?g. }

• W2257277670 endingPage "40" @default.
• W2257277670 startingPage "31" @default.
• W2257277670 abstract "Skin is commonly stored frozen and then thawed prior to use for in vitro permeation experiments. Does frozen storage of skin alter its barrier property? Numerous studies have found contradictory answers to this question. In this study, the steady-state flux and lag time of diethyl phthalate (DEP) were measured for fresh human skin and skin frozen at -85°C for 1, 2, 3, 6, 9, 12, and 18 months with 10% glycerol as a cryoprotective agent. No significant differences in steady-state flux were found between fresh and previously frozen samples (p = 0.6). For lag time, a significant (p = 0.002) difference was found among all groups, but comparisons with fresh skin were not significant. Does glycerol have a cryoprotective effect? The steady-state flux and lag time of DEP and caffeine were measured through human skin stored at -85°C for up to 12 months with and without 10% glycerol. No significant differences in steady-state flux or lag time were found between samples stored with or without glycerol for either DEP or caffeine (p ≥ 0.17). These findings support the use of frozen skin to measure the passive permeation of chemicals in studies unconcerned with viability and metabolism. Published by S. Karger AG, Basel." @default.
• W2257277670 created "2016-06-24" @default.
• W2257277670 creator A5053686544 @default.
• W2257277670 creator A5075466181 @default.
• W2257277670 date "2015-11-26" @default.
• W2257277670 modified "2023-10-01" @default.
• W2257277670 title "Effect of Frozen Human Epidermis Storage Duration and Cryoprotectant on Barrier Function Using Two Model Compounds" @default.
• W2257277670 cites W1965614063 @default.
• W2257277670 cites W1968263314 @default.
• W2257277670 cites W1968762102 @default.
• W2257277670 cites W1972085619 @default.
• W2257277670 cites W1978578590 @default.
• W2257277670 cites W1979994660 @default.
• W2257277670 cites W1982794841 @default.
• W2257277670 cites W1988843459 @default.
• W2257277670 cites W2004716171 @default.
• W2257277670 cites W2016081083 @default.
• W2257277670 cites W2021921386 @default.
• W2257277670 cites W2030112081 @default.
• W2257277670 cites W2030638678 @default.
• W2257277670 cites W2031577994 @default.
• W2257277670 cites W2032766399 @default.
• W2257277670 cites W2041423909 @default.
• W2257277670 cites W2044564175 @default.
• W2257277670 cites W2045800643 @default.
• W2257277670 cites W2058776273 @default.
• W2257277670 cites W2089229095 @default.
• W2257277670 cites W2090508449 @default.
• W2257277670 cites W2091247610 @default.
• W2257277670 cites W2095067107 @default.
• W2257277670 cites W2101453828 @default.
• W2257277670 cites W2116276451 @default.
• W2257277670 cites W2125553820 @default.
• W2257277670 cites W2138540008 @default.
• W2257277670 cites W2142010077 @default.
• W2257277670 cites W2150802401 @default.
• W2257277670 cites W2161247257 @default.
• W2257277670 cites W2461979478 @default.
• W2257277670 cites W31717292 @default.
• W2257277670 cites W4246009666 @default.
• W2257277670 doi "https://doi.org/10.1159/000441038" @default.
• W2257277670 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4742402" @default.
• W2257277670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26606593" @default.
• W2257277670 hasPublicationYear "2015" @default.
• W2257277670 type Work @default.
• W2257277670 sameAs 2257277670 @default.
• W2257277670 citedByCount "31" @default.
• W2257277670 countsByYear W22572776702016 @default.
• W2257277670 countsByYear W22572776702017 @default.
• W2257277670 countsByYear W22572776702018 @default.
• W2257277670 countsByYear W22572776702019 @default.
• W2257277670 countsByYear W22572776702020 @default.
• W2257277670 countsByYear W22572776702021 @default.
• W2257277670 countsByYear W22572776702022 @default.
• W2257277670 countsByYear W22572776702023 @default.
• W2257277670 crossrefType "journal-article" @default.
• W2257277670 hasAuthorship W2257277670A5053686544 @default.
• W2257277670 hasAuthorship W2257277670A5075466181 @default.
• W2257277670 hasBestOaLocation W22572776702 @default.
• W2257277670 hasConcept C134018914 @default.
• W2257277670 hasConcept C147789679 @default.
• W2257277670 hasConcept C179933525 @default.
• W2257277670 hasConcept C185592680 @default.
• W2257277670 hasConcept C196843134 @default.
• W2257277670 hasConcept C2777459323 @default.
• W2257277670 hasConcept C2778500429 @default.
• W2257277670 hasConcept C2780881558 @default.
• W2257277670 hasConcept C41625074 @default.
• W2257277670 hasConcept C43617362 @default.
• W2257277670 hasConcept C50670333 @default.
• W2257277670 hasConcept C54355233 @default.
• W2257277670 hasConcept C55493867 @default.
• W2257277670 hasConcept C68528507 @default.
• W2257277670 hasConcept C8171440 @default.
• W2257277670 hasConcept C86803240 @default.
• W2257277670 hasConcept C95444343 @default.
• W2257277670 hasConceptScore W2257277670C134018914 @default.
• W2257277670 hasConceptScore W2257277670C147789679 @default.
• W2257277670 hasConceptScore W2257277670C179933525 @default.
• W2257277670 hasConceptScore W2257277670C185592680 @default.
• W2257277670 hasConceptScore W2257277670C196843134 @default.
• W2257277670 hasConceptScore W2257277670C2777459323 @default.
• W2257277670 hasConceptScore W2257277670C2778500429 @default.
• W2257277670 hasConceptScore W2257277670C2780881558 @default.
• W2257277670 hasConceptScore W2257277670C41625074 @default.
• W2257277670 hasConceptScore W2257277670C43617362 @default.
• W2257277670 hasConceptScore W2257277670C50670333 @default.
• W2257277670 hasConceptScore W2257277670C54355233 @default.
• W2257277670 hasConceptScore W2257277670C55493867 @default.
• W2257277670 hasConceptScore W2257277670C68528507 @default.
• W2257277670 hasConceptScore W2257277670C8171440 @default.
• W2257277670 hasConceptScore W2257277670C86803240 @default.
• W2257277670 hasConceptScore W2257277670C95444343 @default.
• W2257277670 hasIssue "1" @default.
• W2257277670 hasLocation W22572776701 @default.
• W2257277670 hasLocation W22572776702 @default.
• W2257277670 hasLocation W22572776703 @default.
• W2257277670 hasLocation W22572776704 @default.

• next