Matches in SemOpenAlex for { <https://semopenalex.org/work/W2257497144> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2257497144 endingPage "1170" @default.
- W2257497144 startingPage "1160" @default.
- W2257497144 abstract "Single-photon emission-computed tomography (SPECT) on intact dogs and humans suggests that one aspect of regional blood flow in the lung (Qr) is independent of gravity, e.g., the gradient in Qr between the core and the periphery. To further evaluate these findings, six anesthetized healthy dogs (approximately 30 kg), two in the supine posture, two in the prone posture, and two suspended in the upright posture, breathing spontaneously, were injected (iv) at end expiration with 20 mCi99mTc-labeled albumin macroaggregates. The animals were killed, their chests were opened, their lungs were removed and dissected free of other tissue, and the blood was drained. The lungs were dried by blowing warm air (50 degrees C) while they were inflated to full capacity for about 18 h. The fully inflated and dry lungs were placed in the supine position and SPECT was performed to determine the three-dimensional distribution of activity. One hundred and twenty projections of the activity in the entire lungs were obtained at 3 degrees steps with a rotating gamma camera and stored in computer memory. Once SPECT was completed, either a coronal slice or a sagittal slice (1 cm thick) was cut and imaged directly by placing it against the gamma camera collimator for 6 min. The tomographic-reconstructed slices revealed that at isogravity, in all body postures, Qr in the central region of the lungs was up to 10 times that in the periphery. Furthermore, the central-peripheral gradient was discernible within the individual lobes. The direct images of slices also confirmed these findings. Although flow inequalities independent of gravity were present, the central region with the highest flow often was closer to the dependent regions of the lungs, suggesting that gravity had some influence on the final distribution. The results suggest that factors other than gravity also play an important role in the distribution of pulmonary blood flow. These factors may be related to the conductance of the vascular pathways that lead to different regions in the lungs." @default.
- W2257497144 created "2016-06-24" @default.
- W2257497144 creator A5006412859 @default.
- W2257497144 creator A5070490476 @default.
- W2257497144 creator A5073977491 @default.
- W2257497144 date "1988-03-01" @default.
- W2257497144 modified "2023-10-15" @default.
- W2257497144 title "Effect of body posture on spatial distribution of pulmonary blood flow" @default.
- W2257497144 doi "https://doi.org/10.1152/jappl.1988.64.3.1160" @default.
- W2257497144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3259226" @default.
- W2257497144 hasPublicationYear "1988" @default.
- W2257497144 type Work @default.
- W2257497144 sameAs 2257497144 @default.
- W2257497144 citedByCount "70" @default.
- W2257497144 countsByYear W22574971442013 @default.
- W2257497144 countsByYear W22574971442014 @default.
- W2257497144 countsByYear W22574971442015 @default.
- W2257497144 countsByYear W22574971442016 @default.
- W2257497144 countsByYear W22574971442018 @default.
- W2257497144 countsByYear W22574971442019 @default.
- W2257497144 countsByYear W22574971442020 @default.
- W2257497144 countsByYear W22574971442022 @default.
- W2257497144 crossrefType "journal-article" @default.
- W2257497144 hasAuthorship W2257497144A5006412859 @default.
- W2257497144 hasAuthorship W2257497144A5070490476 @default.
- W2257497144 hasAuthorship W2257497144A5073977491 @default.
- W2257497144 hasConcept C105702510 @default.
- W2257497144 hasConcept C120665830 @default.
- W2257497144 hasConcept C121332964 @default.
- W2257497144 hasConcept C125567185 @default.
- W2257497144 hasConcept C126322002 @default.
- W2257497144 hasConcept C126838900 @default.
- W2257497144 hasConcept C13483470 @default.
- W2257497144 hasConcept C158846371 @default.
- W2257497144 hasConcept C163716698 @default.
- W2257497144 hasConcept C178910020 @default.
- W2257497144 hasConcept C2777714996 @default.
- W2257497144 hasConcept C2779200277 @default.
- W2257497144 hasConcept C2779610220 @default.
- W2257497144 hasConcept C2989005 @default.
- W2257497144 hasConcept C39300077 @default.
- W2257497144 hasConcept C71924100 @default.
- W2257497144 hasConceptScore W2257497144C105702510 @default.
- W2257497144 hasConceptScore W2257497144C120665830 @default.
- W2257497144 hasConceptScore W2257497144C121332964 @default.
- W2257497144 hasConceptScore W2257497144C125567185 @default.
- W2257497144 hasConceptScore W2257497144C126322002 @default.
- W2257497144 hasConceptScore W2257497144C126838900 @default.
- W2257497144 hasConceptScore W2257497144C13483470 @default.
- W2257497144 hasConceptScore W2257497144C158846371 @default.
- W2257497144 hasConceptScore W2257497144C163716698 @default.
- W2257497144 hasConceptScore W2257497144C178910020 @default.
- W2257497144 hasConceptScore W2257497144C2777714996 @default.
- W2257497144 hasConceptScore W2257497144C2779200277 @default.
- W2257497144 hasConceptScore W2257497144C2779610220 @default.
- W2257497144 hasConceptScore W2257497144C2989005 @default.
- W2257497144 hasConceptScore W2257497144C39300077 @default.
- W2257497144 hasConceptScore W2257497144C71924100 @default.
- W2257497144 hasIssue "3" @default.
- W2257497144 hasLocation W22574971441 @default.
- W2257497144 hasLocation W22574971442 @default.
- W2257497144 hasOpenAccess W2257497144 @default.
- W2257497144 hasPrimaryLocation W22574971441 @default.
- W2257497144 hasRelatedWork W1986332952 @default.
- W2257497144 hasRelatedWork W2028241068 @default.
- W2257497144 hasRelatedWork W2051439894 @default.
- W2257497144 hasRelatedWork W2060729109 @default.
- W2257497144 hasRelatedWork W2127080520 @default.
- W2257497144 hasRelatedWork W2234765395 @default.
- W2257497144 hasRelatedWork W2330801393 @default.
- W2257497144 hasRelatedWork W2361563337 @default.
- W2257497144 hasRelatedWork W2531929091 @default.
- W2257497144 hasRelatedWork W1847705498 @default.
- W2257497144 hasVolume "64" @default.
- W2257497144 isParatext "false" @default.
- W2257497144 isRetracted "false" @default.
- W2257497144 magId "2257497144" @default.
- W2257497144 workType "article" @default.