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- W2257625229 abstract "Long noncoding RNAs in gastric cancer: functions and clinical applications Jiajun Wang,* Jingxu Sun,* Jun Wang, Yongxi Song, Peng Gao, Jinxin Shi, Ping Chen, Zhenning Wang Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People’s Republic of China *These authors contributed equally to this work Abstract: Over the last two decades, genome-wide studies have revealed that only a small fraction of the human genome encodes proteins; long noncoding RNAs (lncRNAs) account for 98% of the total genome. These RNA molecules, which are >200 nt in length, play important roles in diverse biological processes, including the immune response, stem cell pluripotency, cell proliferation, apoptosis, differentiation, invasion, and metastasis by regulating gene expression at the epigenetic, transcriptional, and posttranscriptional levels. However, the detailed molecular mechanisms underlying lncRNA function are only partially understood. Recent studies showed that many lncRNAs are aberrantly expressed in gastric cancer (GC) tissues, gastric juice, plasma, and cells, and these alterations are linked to the occurrence, progression, and outcome of GC. Here, we review the current knowledge of the biological functions and clinical aspects of lncRNAs in GC. Keywords: long noncoding RNA, gastric cancer, biomarker, target therapy" @default.
- W2257625229 created "2016-06-24" @default.
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- W2257625229 date "2016-02-01" @default.
- W2257625229 modified "2023-09-27" @default.
- W2257625229 title "Long noncoding RNAs in gastric cancer: functions and clinical applications" @default.
- W2257625229 cites W1435045704 @default.
- W2257625229 cites W1488201557 @default.
- W2257625229 cites W1529132978 @default.
- W2257625229 cites W1552793640 @default.
- W2257625229 cites W1587725355 @default.
- W2257625229 cites W1603050207 @default.
- W2257625229 cites W1606879372 @default.
- W2257625229 cites W165825322 @default.
- W2257625229 cites W167012439 @default.
- W2257625229 cites W1762688284 @default.
- W2257625229 cites W183341991 @default.
- W2257625229 cites W1852995033 @default.
- W2257625229 cites W1856228646 @default.
- W2257625229 cites W1899418860 @default.
- W2257625229 cites W1916533195 @default.
- W2257625229 cites W1964713316 @default.
- W2257625229 cites W1968482426 @default.
- W2257625229 cites W1969968365 @default.
- W2257625229 cites W1972017985 @default.
- W2257625229 cites W1974883337 @default.
- W2257625229 cites W1974964473 @default.
- W2257625229 cites W1975029438 @default.
- W2257625229 cites W1975213539 @default.
- W2257625229 cites W1975814239 @default.
- W2257625229 cites W1981162875 @default.
- W2257625229 cites W1981989535 @default.
- W2257625229 cites W1985141701 @default.
- W2257625229 cites W1985770875 @default.
- W2257625229 cites W1988062399 @default.
- W2257625229 cites W1988447508 @default.
- W2257625229 cites W1989455675 @default.
- W2257625229 cites W1991823590 @default.
- W2257625229 cites W1995022961 @default.
- W2257625229 cites W1995547461 @default.
- W2257625229 cites W1996089895 @default.
- W2257625229 cites W1997310447 @default.
- W2257625229 cites W1999114313 @default.
- W2257625229 cites W1999616263 @default.
- W2257625229 cites W2001009471 @default.
- W2257625229 cites W2003553455 @default.
- W2257625229 cites W2008350439 @default.
- W2257625229 cites W2010691380 @default.
- W2257625229 cites W2013719305 @default.
- W2257625229 cites W2021063653 @default.
- W2257625229 cites W2032327846 @default.
- W2257625229 cites W2034282509 @default.
- W2257625229 cites W2035086461 @default.
- W2257625229 cites W2039156362 @default.
- W2257625229 cites W2052039819 @default.
- W2257625229 cites W2053135029 @default.
- W2257625229 cites W2058334853 @default.
- W2257625229 cites W2060430981 @default.
- W2257625229 cites W2061261750 @default.
- W2257625229 cites W2064259001 @default.
- W2257625229 cites W2069122497 @default.
- W2257625229 cites W2073055866 @default.
- W2257625229 cites W2074847683 @default.
- W2257625229 cites W2078526959 @default.
- W2257625229 cites W2079565353 @default.
- W2257625229 cites W2085436890 @default.
- W2257625229 cites W2091161969 @default.
- W2257625229 cites W2094593141 @default.
- W2257625229 cites W2097398875 @default.
- W2257625229 cites W2101920478 @default.
- W2257625229 cites W2101926514 @default.
- W2257625229 cites W2102203437 @default.
- W2257625229 cites W2103339837 @default.
- W2257625229 cites W2105726520 @default.
- W2257625229 cites W2107716254 @default.
- W2257625229 cites W2109093191 @default.
- W2257625229 cites W2110356447 @default.
- W2257625229 cites W2111119573 @default.
- W2257625229 cites W2124996418 @default.
- W2257625229 cites W2125502129 @default.
- W2257625229 cites W2127744901 @default.
- W2257625229 cites W2128079038 @default.
- W2257625229 cites W2128876691 @default.
- W2257625229 cites W2129478331 @default.
- W2257625229 cites W2130765537 @default.
- W2257625229 cites W2132444060 @default.
- W2257625229 cites W2136222002 @default.
- W2257625229 cites W2139709116 @default.
- W2257625229 cites W2141497782 @default.
- W2257625229 cites W2141831115 @default.
- W2257625229 cites W2146573461 @default.