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• W2257635864 endingPage "175" @default.
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• W2257635864 abstract "Radiolabelled choline positron emission tomography has changed the management of prostate cancer patients. However, new emerging radiopharmaceutical agents, like radiolabelled prostate specific membrane antigen, and new promising hybrid imaging will begin new challenges in the diagnostic field. The continuous evolution in nuclear medicine has led to the improvement in the detection of recurrent prostate cancer (PCa), particularly distant metastases. New horizons have been opened for radiolabelled choline positron emission tomography (PET)/computed tomography (CT) as a guide for salvage therapy or for the assessment of systemic therapies. In addition, new tracers and imaging tools have been recently tested, providing important information for the management of PCa patients. Herein we discuss: (1) the available evidence in literature on radiolabelled choline PET and their recent indications, (2) the role of alternative radiopharmaceutical agents, and (3) the advantages of a recent hybrid imaging device (PET/magnetic resonance imaging) in PCa. Data from recently published (2010–2015), original articles concerning the role of choline PET/CT, new emerging radiotracers, and a new imaging device are analysed. This review is reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. In the restaging phase, the detection rate of choline PET varies between 4% and 97%, mainly depending on the site of recurrence and prostate-specific antigen levels. Both 68gallium (68Ga)-prostate specific membrane antigen and 18F-fluciclovine are shown to be more accurate in the detection of recurrent disease as compared with radiolabelled choline PET/CT. Particularly, Ga68-PSMA has a detection rate of 50% and 68%, respectively for prostate-specific antigen levels < 0.5 ng/ml and 0.5–2 ng/ml. Moreover, 68Ga- PSMA PET/magnetic resonance imaging demonstrated a particularly higher accuracy in detecting PCa than PET/CT. New tracers, such as radiolabelled bombesin or urokinase-type plasminogen activator receptor, are promising, but few data in clinical practice are available today. Some limitations emerge from the published papers, both for radiolabelled choline PET/CT and also for new radiopharmaceutical agents. Efforts are still needed to enhance the impact of published data in the world of oncology, in particular when new radiopharmaceuticals are introduced into the clinical arena. In the present review, the authors summarise the last evidences in clinical practice for the assessment of prostate cancer, by using nuclear medicine modalities, like positron emission tomography/computed tomography and positron emission tomography/magnetic resonance imaging." @default.
• W2257635864 created "2016-06-24" @default.
• W2257635864 creator A5004351505 @default.
• W2257635864 creator A5009200179 @default.
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• W2257635864 creator A5087431312 @default.
• W2257635864 date "2016-07-01" @default.
• W2257635864 modified "2023-09-28" @default.
• W2257635864 title "New Clinical Indications for 18 F/ 11 C-choline, New Tracers for Positron Emission Tomography and a Promising Hybrid Device for Prostate Cancer Staging: A Systematic Review of the Literature" @default.
• W2257635864 cites W101610969 @default.
• W2257635864 cites W1232915009 @default.
• W2257635864 cites W129361165 @default.
• W2257635864 cites W1462779669 @default.
• W2257635864 cites W1490266165 @default.
• W2257635864 cites W1512308415 @default.
• W2257635864 cites W1517749817 @default.
• W2257635864 cites W1544486867 @default.
• W2257635864 cites W1566558399 @default.
• W2257635864 cites W1756490717 @default.
• W2257635864 cites W1900676315 @default.
• W2257635864 cites W1903999661 @default.
• W2257635864 cites W1919117211 @default.
• W2257635864 cites W1965751182 @default.
• W2257635864 cites W1966225993 @default.
• W2257635864 cites W1970062306 @default.
• W2257635864 cites W1973596696 @default.
• W2257635864 cites W1973717257 @default.
• W2257635864 cites W1980978537 @default.
• W2257635864 cites W1982447130 @default.
• W2257635864 cites W1989672749 @default.
• W2257635864 cites W1991291077 @default.
• W2257635864 cites W1992086886 @default.
• W2257635864 cites W1994260842 @default.
• W2257635864 cites W1994463565 @default.
• W2257635864 cites W1996043450 @default.
• W2257635864 cites W1998345392 @default.
• W2257635864 cites W2002301736 @default.
• W2257635864 cites W2014999922 @default.
• W2257635864 cites W2016310186 @default.
• W2257635864 cites W2016451441 @default.
• W2257635864 cites W2016973566 @default.
• W2257635864 cites W2019026418 @default.
• W2257635864 cites W2022108741 @default.
• W2257635864 cites W2022381592 @default.
• W2257635864 cites W2029203157 @default.
• W2257635864 cites W2039499300 @default.
• W2257635864 cites W2043839162 @default.
• W2257635864 cites W2046001005 @default.
• W2257635864 cites W2051871489 @default.
• W2257635864 cites W2058426653 @default.
• W2257635864 cites W2061595656 @default.
• W2257635864 cites W2065013125 @default.
• W2257635864 cites W2065727101 @default.
• W2257635864 cites W2066588899 @default.
• W2257635864 cites W2066758446 @default.
• W2257635864 cites W2068601916 @default.
• W2257635864 cites W2078420820 @default.
• W2257635864 cites W2080553658 @default.
• W2257635864 cites W2081569633 @default.
• W2257635864 cites W2085086101 @default.
• W2257635864 cites W2085776136 @default.
• W2257635864 cites W2094870141 @default.
• W2257635864 cites W2096981363 @default.
• W2257635864 cites W2099169865 @default.
• W2257635864 cites W2101301092 @default.
• W2257635864 cites W2107638293 @default.
• W2257635864 cites W2109850844 @default.
• W2257635864 cites W2110141997 @default.
• W2257635864 cites W2110429519 @default.
• W2257635864 cites W2112113117 @default.
• W2257635864 cites W2117441254 @default.
• W2257635864 cites W2117793166 @default.
• W2257635864 cites W2120873855 @default.
• W2257635864 cites W2125245370 @default.
• W2257635864 cites W2129260701 @default.
• W2257635864 cites W2131498353 @default.
• W2257635864 cites W2131970757 @default.
• W2257635864 cites W2134818418 @default.
• W2257635864 cites W2137670219 @default.
• W2257635864 cites W2139529507 @default.
• W2257635864 cites W2140464580 @default.
• W2257635864 cites W2143802196 @default.
• W2257635864 cites W2145801780 @default.
• W2257635864 cites W2147309339 @default.
• W2257635864 cites W2148486277 @default.
• W2257635864 cites W2149269178 @default.
• W2257635864 cites W2154506800 @default.
• W2257635864 cites W2156549595 @default.
• W2257635864 cites W2156923673 @default.
• W2257635864 cites W2159959275 @default.
• W2257635864 cites W2188271985 @default.
• W2257635864 cites W2325133960 @default.
• W2257635864 cites W2331613680 @default.

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