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- W22576799 endingPage "43" @default.
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- W22576799 abstract "Adult hippocampal neurogenesis, the birth of new neurons in the dentate gyrus of the adult brain, can be regulated by stress and antidepressant treatment, and has consistently been implicated in the behavioral neurobiology of stress-related disorders, especially depression and anxiety. A reciprocal relationship between hippocampal neurogenesis and the hypothalamus–pituitary–adrenal (HPA) axis has recently been suggested, which may play a crucial role in the development and in the resolution of depressive symptoms. This chapter will review some of the existing evidence for stress- and antidepressant-induced changes in adult hippocampal neurogenesis, and critically evaluate the behavioral effects of these changes for depression and anxiety. The potential role of neurogenesis as a neurobiological mechanism for sustained remission from depressive symptoms will be discussed, integrating existing data from clinical studies, animal work, and cellular models. The effect of glucocorticoid hormones and the glucocorticoid receptor (GR) will thereby be evaluated as a central mechanism by which stress and antidepressant may exert their opposing effects on neurogenesis, and ultimately, on mood and behavior." @default.
- W22576799 created "2016-06-24" @default.
- W22576799 creator A5090345115 @default.
- W22576799 date "2014-01-01" @default.
- W22576799 modified "2023-10-17" @default.
- W22576799 title "Adult Hippocampal Neurogenesis in Depression: Behavioral Implications and Regulation by the Stress System" @default.
- W22576799 cites W1518574168 @default.
- W22576799 cites W1761323037 @default.
- W22576799 cites W1964173716 @default.
- W22576799 cites W1965355495 @default.
- W22576799 cites W1967290761 @default.
- W22576799 cites W1967340797 @default.
- W22576799 cites W1967913855 @default.
- W22576799 cites W1975760153 @default.
- W22576799 cites W1977650085 @default.
- W22576799 cites W1979612418 @default.
- W22576799 cites W1980374662 @default.
- W22576799 cites W1980499453 @default.
- W22576799 cites W1981724466 @default.
- W22576799 cites W1982313674 @default.
- W22576799 cites W1989140838 @default.
- W22576799 cites W1989145093 @default.
- W22576799 cites W1989432198 @default.
- W22576799 cites W1998154386 @default.
- W22576799 cites W2000273941 @default.
- W22576799 cites W2004227284 @default.
- W22576799 cites W2004366364 @default.
- W22576799 cites W2007636259 @default.
- W22576799 cites W2007746109 @default.
- W22576799 cites W2014099101 @default.
- W22576799 cites W2019316537 @default.
- W22576799 cites W2019757402 @default.
- W22576799 cites W2021551531 @default.
- W22576799 cites W2022372660 @default.
- W22576799 cites W2022571097 @default.
- W22576799 cites W2023343492 @default.
- W22576799 cites W2025129891 @default.
- W22576799 cites W2027122202 @default.
- W22576799 cites W2030772288 @default.
- W22576799 cites W2034694738 @default.
- W22576799 cites W2035647952 @default.
- W22576799 cites W2038487059 @default.
- W22576799 cites W2039193217 @default.
- W22576799 cites W2039201970 @default.
- W22576799 cites W2039808373 @default.
- W22576799 cites W2040465695 @default.
- W22576799 cites W2043893734 @default.
- W22576799 cites W2044137472 @default.
- W22576799 cites W2049539653 @default.
- W22576799 cites W2054818459 @default.
- W22576799 cites W2055747883 @default.
- W22576799 cites W2059565695 @default.
- W22576799 cites W2060159413 @default.
- W22576799 cites W2060503785 @default.
- W22576799 cites W2060644077 @default.
- W22576799 cites W2060709606 @default.
- W22576799 cites W2060918456 @default.
- W22576799 cites W2063379674 @default.
- W22576799 cites W2064424963 @default.
- W22576799 cites W2066457796 @default.
- W22576799 cites W2066831309 @default.
- W22576799 cites W2067856703 @default.
- W22576799 cites W2068607973 @default.
- W22576799 cites W2069281265 @default.
- W22576799 cites W2073216156 @default.
- W22576799 cites W2076012260 @default.
- W22576799 cites W2078957832 @default.
- W22576799 cites W2080795205 @default.
- W22576799 cites W2082177415 @default.
- W22576799 cites W2092499931 @default.
- W22576799 cites W2096160341 @default.
- W22576799 cites W2097408153 @default.
- W22576799 cites W2101585433 @default.
- W22576799 cites W2110552899 @default.
- W22576799 cites W2128944765 @default.
- W22576799 cites W2130844101 @default.
- W22576799 cites W2132358310 @default.
- W22576799 cites W2132993734 @default.
- W22576799 cites W2133565799 @default.
- W22576799 cites W2134038068 @default.
- W22576799 cites W2136801447 @default.
- W22576799 cites W2136863044 @default.
- W22576799 cites W2141701184 @default.
- W22576799 cites W2142525943 @default.
- W22576799 cites W2146316688 @default.
- W22576799 cites W2148099028 @default.
- W22576799 cites W2148239264 @default.
- W22576799 cites W2149677176 @default.
- W22576799 cites W2151340091 @default.
- W22576799 cites W2151595908 @default.
- W22576799 cites W2156404675 @default.
- W22576799 cites W2166687069 @default.
- W22576799 cites W2167629442 @default.
- W22576799 cites W2171244012 @default.
- W22576799 cites W59530324 @default.
- W22576799 doi "https://doi.org/10.1007/7854_2014_275" @default.
- W22576799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24478038" @default.
- W22576799 hasPublicationYear "2014" @default.