FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2258068897> ?p ?o ?g. }

• W2258068897 endingPage "341" @default.
• W2258068897 startingPage "331" @default.
• W2258068897 abstract "<h3>Background:</h3> The human brain is organized into functionally distinct modules of which interactions constitute the human functional connectome. Accumulating evidence has implicated perturbations in the patterns of brain connectivity across a range of neurologic and neuropsychiatric disorders, but little is known about diagnostic specificity. Schizophrenia and bipolar disorders are severe mental disorders with partly overlapping symptomatology. Neuroimaging has demonstrated brain network disintegration in the pathophysiologies; however, to which degree the 2 diagnoses present with overlapping abnormalities remains unclear. <h3>Methods:</h3> We collected resting-state fMRI data from patients with schizophrenia or bipolar disorder and from healthy controls. Aiming to characterize connectivity differences across 2 severe mental disorders, we derived global functional connectivity using eigenvector centrality mapping, which allows for regional inference of centrality or importance in the brain network. <h3>Results:</h3> Seventy-one patients with schizophrenia, 43 with bipolar disorder and 196 healthy controls participated in our study. We found significant effects of diagnosis in 12 clusters, where pairwise comparisons showed decreased global connectivity in high-centrality clusters: sensory regions in patients with schizophrenia and subcortical regions in both patient groups. Increased connectivity occurred in frontal and parietal clusters in patients with schizophrenia, with intermediate effects in those with bipolar disorder. Patient groups differed in most cortical clusters, with the strongest effects in sensory regions. <h3>Limitations:</h3> Methodological concerns of in-scanner motion and the use of full correlation measures may make analyses more vulnerable to noise. <h3>Conclusion:</h3> Our results show decreased eigenvector centrality of limbic structures in both patient groups and in sensory regions in patients with schizophrenia as well as increased centrality in frontal and parietal regions in both groups, with stronger effects in patients with schizophrenia." @default.
• W2258068897 created "2016-06-24" @default.
• W2258068897 creator A5002668347 @default.
• W2258068897 creator A5006168982 @default.
• W2258068897 creator A5016103514 @default.
• W2258068897 creator A5020215901 @default.
• W2258068897 creator A5023206472 @default.
• W2258068897 creator A5025645521 @default.
• W2258068897 creator A5038059939 @default.
• W2258068897 creator A5038692125 @default.
• W2258068897 creator A5086249256 @default.
• W2258068897 date "2016-09-01" @default.
• W2258068897 modified "2023-10-18" @default.
• W2258068897 title "Global brain connectivity alterations in patients with schizophrenia and bipolar spectrum disorders" @default.
• W2258068897 cites W1201211098 @default.
• W2258068897 cites W1497201830 @default.
• W2258068897 cites W1509285273 @default.
• W2258068897 cites W1905519752 @default.
• W2258068897 cites W1930790356 @default.
• W2258068897 cites W1978298437 @default.
• W2258068897 cites W1984615306 @default.
• W2258068897 cites W1998679999 @default.
• W2258068897 cites W1999384062 @default.
• W2258068897 cites W1999653836 @default.
• W2258068897 cites W1999747923 @default.
• W2258068897 cites W2000433175 @default.
• W2258068897 cites W2004293194 @default.
• W2258068897 cites W2005371521 @default.
• W2258068897 cites W2005476331 @default.
• W2258068897 cites W2007002607 @default.
• W2258068897 cites W2008607322 @default.
• W2258068897 cites W2020044743 @default.
• W2258068897 cites W2041325253 @default.
• W2258068897 cites W2041951497 @default.
• W2258068897 cites W2046557060 @default.
• W2258068897 cites W2047453615 @default.
• W2258068897 cites W2047975465 @default.
• W2258068897 cites W2052615191 @default.
• W2258068897 cites W2052644075 @default.
• W2258068897 cites W2076805502 @default.
• W2258068897 cites W2077716286 @default.
• W2258068897 cites W2092784010 @default.
• W2258068897 cites W2093540790 @default.
• W2258068897 cites W2095491050 @default.
• W2258068897 cites W2098597355 @default.
• W2258068897 cites W2104016179 @default.
• W2258068897 cites W2106104226 @default.
• W2258068897 cites W2114044404 @default.
• W2258068897 cites W2118366819 @default.
• W2258068897 cites W2123703395 @default.
• W2258068897 cites W2127070446 @default.
• W2258068897 cites W2136199096 @default.
• W2258068897 cites W2136532493 @default.
• W2258068897 cites W2138905229 @default.
• W2258068897 cites W2139870060 @default.
• W2258068897 cites W2140606211 @default.
• W2258068897 cites W2140884917 @default.
• W2258068897 cites W2143895814 @default.
• W2258068897 cites W2151721316 @default.
• W2258068897 cites W2152958283 @default.
• W2258068897 cites W2157446241 @default.
• W2258068897 cites W2159862192 @default.
• W2258068897 cites W2161493176 @default.
• W2258068897 cites W2977883299 @default.
• W2258068897 cites W4249539254 @default.
• W2258068897 doi "https://doi.org/10.1503/jpn.150159" @default.
• W2258068897 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5008922" @default.
• W2258068897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26854755" @default.
• W2258068897 hasPublicationYear "2016" @default.
• W2258068897 type Work @default.
• W2258068897 sameAs 2258068897 @default.
• W2258068897 citedByCount "48" @default.
• W2258068897 countsByYear W22580688972016 @default.
• W2258068897 countsByYear W22580688972017 @default.
• W2258068897 countsByYear W22580688972018 @default.
• W2258068897 countsByYear W22580688972019 @default.
• W2258068897 countsByYear W22580688972020 @default.
• W2258068897 countsByYear W22580688972021 @default.
• W2258068897 countsByYear W22580688972022 @default.
• W2258068897 countsByYear W22580688972023 @default.
• W2258068897 crossrefType "journal-article" @default.
• W2258068897 hasAuthorship W2258068897A5002668347 @default.
• W2258068897 hasAuthorship W2258068897A5006168982 @default.
• W2258068897 hasAuthorship W2258068897A5016103514 @default.
• W2258068897 hasAuthorship W2258068897A5020215901 @default.
• W2258068897 hasAuthorship W2258068897A5023206472 @default.
• W2258068897 hasAuthorship W2258068897A5025645521 @default.
• W2258068897 hasAuthorship W2258068897A5038059939 @default.
• W2258068897 hasAuthorship W2258068897A5038692125 @default.
• W2258068897 hasAuthorship W2258068897A5086249256 @default.
• W2258068897 hasBestOaLocation W22580688971 @default.
• W2258068897 hasConcept C118552586 @default.
• W2258068897 hasConcept C15744967 @default.
• W2258068897 hasConcept C169760540 @default.
• W2258068897 hasConcept C169900460 @default.
• W2258068897 hasConcept C2776174506 @default.
• W2258068897 hasConcept C2776412080 @default.
• W2258068897 hasConcept C3018011982 @default.

• next